Detailed information NTG0549019

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: J4Q30_RS06045
• Genome accession: NZ_CP071917
• Coordinates: 1173137..1174090 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 19A-19339
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1168137..1179090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q30_RS06020 (J4Q30_06025)	-	1168618..1168713 (-)	96	Protein_1207	IS630 family transposase	-
J4Q30_RS06025 (J4Q30_06030)	-	1169126..1169467 (+)	342	Protein_1208	transposase	-
J4Q30_RS06030 (J4Q30_06035)	prsA	1169584..1170525 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
J4Q30_RS06035 (J4Q30_06040)	-	1170592..1171305 (-)	714	WP_000230400.1	O-methyltransferase	-
J4Q30_RS06040 (J4Q30_06045)	pepF	1171307..1173118 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
J4Q30_RS06045 (J4Q30_06050)	coiA	1173137..1174090 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
J4Q30_RS06050 (J4Q30_06055)	tehB	1174163..1175023 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
J4Q30_RS06055 (J4Q30_06060)	smpB	1175039..1175506 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
J4Q30_RS06060 (J4Q30_06065)	rnr	1175469..1177823 (-)	2355	WP_000654886.1	ribonuclease R	-
J4Q30_RS06065 (J4Q30_06070)	secG	1177925..1178158 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
J4Q30_RS06070 (J4Q30_06075)	rpmG	1178198..1178347 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=549019 J4Q30_RS06045 WP_000495909.1 1173137..1174090(-) (coiA) [Streptococcus pneumoniae strain 19A-19339]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=549019 J4Q30_RS06045 WP_000495909.1 1173137..1174090(-) (coiA) [Streptococcus pneumoniae strain 19A-19339]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435