Detailed information NTG0548971

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: J4Q32_RS09455
• Genome accession: NZ_CP071916
• Coordinates: 1832050..1833087 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 19A-19087
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1827050..1838087

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q32_RS09430 (J4Q32_09425)	-	1827789..1829120 (-)	1332	WP_000390039.1	hemolysin family protein	-
J4Q32_RS09435 (J4Q32_09430)	endA	1829411..1830235 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
J4Q32_RS09440 (J4Q32_09435)	-	1830274..1830462 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
J4Q32_RS09445 (J4Q32_09440)	murA	1830455..1831738 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J4Q32_RS09450 (J4Q32_09445)	-	1831762..1831992 (-)	231	WP_000615437.1	DUF1146 family protein	-
J4Q32_RS09455 (J4Q32_09450)	sepM	1832050..1833087 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
J4Q32_RS09460 (J4Q32_09455)	coaD	1833071..1833559 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
J4Q32_RS09465 (J4Q32_09460)	rsmD	1833549..1834088 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
J4Q32_RS09470 (J4Q32_09465)	asnA	1834153..1835145 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
J4Q32_RS09475 (J4Q32_09470)	-	1835257..1835940 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
J4Q32_RS09480 (J4Q32_09475)	-	1835996..1836736 (-)	741	WP_000152701.1	RNA methyltransferase	-
J4Q32_RS09485 (J4Q32_09480)	-	1836770..1837048 (+)	279	WP_001174613.1	acylphosphatase	-
J4Q32_RS09490 (J4Q32_09485)	yidC	1837126..1838052 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=548971 J4Q32_RS09455 WP_000727280.1 1832050..1833087(-) (sepM) [Streptococcus pneumoniae strain 19A-19087]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=548971 J4Q32_RS09455 WP_000727280.1 1832050..1833087(-) (sepM) [Streptococcus pneumoniae strain 19A-19087]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591