Detailed information NTG0548074

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: CSB63_RS08135
• Genome accession: NZ_CP089060
• Coordinates: 1532500..1534653 (-)
• Length: 717 a.a.
• NCBI ID: WP_255135330.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CH8
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1527500..1539653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB63_RS08100 (CSB63_1701)	-	1527620..1527850 (-)	231	WP_011226494.1	bacteriocin class II family protein	-
CSB63_RS08105 (CSB63_1702)	-	1528206..1528406 (-)	201	WP_011681569.1	hypothetical protein	-
CSB63_RS08110 (CSB63_1703)	-	1528425..1528601 (-)	177	WP_011681570.1	Blp family class II bacteriocin	-
CSB63_RS08115 (CSB63_1704)	-	1528852..1529589 (+)	738	WP_134973464.1	LytR/AlgR family response regulator transcription factor	-
CSB63_RS08120	comD/blpH	1530120..1530923 (+)	804	WP_223899638.1	ATP-binding protein	Regulator
CSB63_RS08125 (CSB63_1706)	-	1530941..1531102 (-)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
CSB63_RS08130 (CSB63_1707)	comB	1531117..1532484 (-)	1368	WP_011681574.1	bacteriocin secretion accessory protein	Regulator
CSB63_RS08135 (CSB63_1708)	comA/nlmT	1532500..1534653 (-)	2154	WP_255135330.1	peptide cleavage/export ABC transporter	Regulator
CSB63_RS08140	-	1535667..1537414 (-)	1748	Protein_1548	ABC transporter ATP-binding protein	-
CSB63_RS08145 (CSB63_1713)	-	1537407..1539164 (-)	1758	WP_024010065.1	ABC transporter ATP-binding protein	-
CSB63_RS08150 (CSB63_1714)	-	1539352..1539558 (-)	207	WP_011681579.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80615.44 Da
• Isoelectric Point: 6.8332

>NTDB_id=548074 CSB63_RS08135 WP_255135330.1 1532500..1534653(-) (comA/nlmT) [Streptococcus thermophilus strain CH8]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDQGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=548074 CSB63_RS08135 WP_255135330.1 1532500..1534653(-) (comA/nlmT) [Streptococcus thermophilus strain CH8]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCAGGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	68.067	99.582	0.678
comA	Streptococcus mitis NCTC 12261	66.245	99.163	0.657
comA	Streptococcus pneumoniae Rx1	65.823	99.163	0.653
comA	Streptococcus pneumoniae D39	65.823	99.163	0.653
comA	Streptococcus pneumoniae R6	65.823	99.163	0.653
comA	Streptococcus mitis SK321	65.541	99.163	0.65
comA	Streptococcus pneumoniae TIGR4	65.401	99.163	0.649
comA	Streptococcus gordonii str. Challis substr. CH1	64.426	99.582	0.642