Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   CSB63_RS07770 Genome accession   NZ_CP089060
Coordinates   1465392..1467497 (-) Length   701 a.a.
NCBI ID   WP_255135265.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CH8     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460392..1472497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB63_RS07735 (CSB63_1624) pptB 1460864..1461898 (-) 1035 WP_372450197.1 ABC transporter permease Regulator
  CSB63_RS07740 (CSB63_1625) pptA 1461898..1462629 (-) 732 WP_084829044.1 ABC transporter ATP-binding protein Regulator
  CSB63_RS07745 (CSB63_1626) - 1462694..1463113 (+) 420 WP_084829045.1 HIT family protein -
  CSB63_RS07750 (CSB63_1627) - 1463110..1463409 (+) 300 WP_084829809.1 hypothetical protein -
  CSB63_RS07755 (CSB63_1628) - 1463460..1464188 (-) 729 WP_134973435.1 hypothetical protein -
  CSB63_RS07760 (CSB63_1629) - 1464204..1464797 (-) 594 WP_134973437.1 DUF4230 domain-containing protein -
  CSB63_RS07765 (CSB63_1630) - 1464856..1464981 (-) 126 WP_011681534.1 hypothetical protein -
  CSB63_RS07770 (CSB63_1631) clpE 1465392..1467497 (-) 2106 WP_255135265.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  CSB63_RS07775 (CSB63_1632) - 1468213..1469304 (-) 1092 WP_134973441.1 nucleotidyltransferase -
  CSB63_RS07780 (CSB63_1633) - 1469311..1470051 (-) 741 WP_280632115.1 class I SAM-dependent DNA methyltransferase -
  CSB63_RS07785 (CSB63_1634) rsfS 1470376..1470729 (-) 354 WP_011227491.1 ribosome silencing factor -
  CSB63_RS07790 (CSB63_1635) yqeK 1470753..1471343 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CSB63_RS07795 (CSB63_1636) - 1471340..1471972 (-) 633 WP_002951698.1 nicotinate-nucleotide adenylyltransferase -
  CSB63_RS07800 (CSB63_1637) yhbY 1472076..1472393 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77394.27 Da        Isoelectric Point: 4.7678

>NTDB_id=548068 CSB63_RS07770 WP_255135265.1 1465392..1467497(-) (clpE) [Streptococcus thermophilus strain CH8]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKIGRN
LTQEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVSGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NPALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMDNHLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNLTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=548068 CSB63_RS07770 WP_255135265.1 1465392..1467497(-) (clpE) [Streptococcus thermophilus strain CH8]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAAATTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAGTGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATCCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGGATAACCATTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTTGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA lid domain (AAA_lid_9)

(257-351)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-235)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.648

100

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

48.848

92.867

0.454
  clpE Streptococcus pneumoniae R6

48.131

91.583

0.441
  clpE Streptococcus pneumoniae Rx1

48.131

91.583

0.441
  clpE Streptococcus pneumoniae D39

48.131

91.583

0.441
  clpE Streptococcus pneumoniae TIGR4

48.05

91.441

0.439
  clpC Bacillus subtilis subsp. subtilis str. 168

44.962

94.864

0.427
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.025

93.01

0.391
  clpC Streptococcus thermophilus LMD-9

43.922

88.017

0.387
  clpC Streptococcus thermophilus LMG 18311

43.76

88.017

0.385
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus mutans UA159

42.765

88.73

0.379