Detailed information    

insolico Bioinformatically predicted

Overview

Name   radA   Type   Machinery gene
Locus tag   JZ789_RS11105 Genome accession   NZ_CP071806
Coordinates   2230119..2231489 (-) Length   456 a.a.
NCBI ID   WP_004298358.1    Uniprot ID   A0A126UJP8
Organism   Streptococcus suis strain GX69     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2232036..2254533 2230119..2231489 flank 547


Gene organization within MGE regions


Location: 2230119..2254533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZ789_RS11105 (JZ789_11020) radA 2230119..2231489 (-) 1371 WP_004298358.1 DNA repair protein RadA Machinery gene
  JZ789_RS11110 (JZ789_11025) - 2231496..2232029 (-) 534 WP_004298356.1 histidine phosphatase family protein -
  JZ789_RS11115 (JZ789_11030) - 2232036..2232479 (-) 444 WP_004298354.1 dUTP diphosphatase -
  JZ789_RS11120 (JZ789_11035) - 2232577..2233722 (-) 1146 WP_226316922.1 site-specific integrase -
  JZ789_RS11125 - 2234189..2234716 (-) 528 WP_226316966.1 helix-turn-helix domain-containing protein -
  JZ789_RS11130 (JZ789_11045) - 2234922..2235122 (+) 201 WP_015647585.1 helix-turn-helix transcriptional regulator -
  JZ789_RS11135 (JZ789_11050) - 2235140..2235838 (+) 699 WP_226316923.1 Rha family transcriptional regulator -
  JZ789_RS11140 (JZ789_11055) - 2235851..2236477 (+) 627 WP_226316924.1 Rha family transcriptional regulator -
  JZ789_RS11145 (JZ789_11060) - 2236574..2236870 (+) 297 WP_099778085.1 hypothetical protein -
  JZ789_RS11150 (JZ789_11065) - 2237237..2237665 (+) 429 WP_226316925.1 hypothetical protein -
  JZ789_RS12085 - 2237665..2237862 (+) 198 WP_407047439.1 hypothetical protein -
  JZ789_RS11155 (JZ789_11070) - 2237872..2238057 (+) 186 WP_226316926.1 hypothetical protein -
  JZ789_RS11160 (JZ789_11075) - 2238054..2238389 (+) 336 WP_226316927.1 hypothetical protein -
  JZ789_RS11165 (JZ789_11080) - 2238382..2238663 (+) 282 WP_226316928.1 XRE family transcriptional regulator -
  JZ789_RS11170 (JZ789_11085) - 2238650..2239450 (+) 801 WP_226316929.1 phage replisome organizer N-terminal domain-containing protein -
  JZ789_RS11175 (JZ789_11090) - 2239463..2240290 (+) 828 WP_226316930.1 ATP-binding protein -
  JZ789_RS11180 (JZ789_11095) - 2240295..2240855 (+) 561 WP_226316931.1 hypothetical protein -
  JZ789_RS11185 - 2240931..2241434 (+) 504 WP_226316932.1 hypothetical protein -
  JZ789_RS11190 (JZ789_11100) - 2241875..2242306 (+) 432 WP_226316933.1 DUF1492 domain-containing protein -
  JZ789_RS11195 (JZ789_11105) - 2243087..2244871 (-) 1785 WP_170244756.1 ABC transporter ATP-binding protein -
  JZ789_RS11200 (JZ789_11110) - 2244872..2246578 (-) 1707 WP_024394878.1 ABC transporter ATP-binding protein -
  JZ789_RS11205 (JZ789_11115) - 2246571..2247020 (-) 450 WP_024387360.1 MarR family winged helix-turn-helix transcriptional regulator -
  JZ789_RS11210 (JZ789_11120) - 2247242..2248258 (+) 1017 WP_012027922.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  JZ789_RS11215 (JZ789_11125) galU 2248303..2249202 (+) 900 WP_004298345.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  JZ789_RS11220 (JZ789_11130) - 2249220..2249897 (-) 678 WP_024387359.1 rhomboid family intramembrane serine protease -
  JZ789_RS11225 (JZ789_11135) - 2249881..2250423 (-) 543 WP_024387358.1 5-formyltetrahydrofolate cyclo-ligase -
  JZ789_RS11230 (JZ789_11140) - 2250464..2251591 (-) 1128 WP_024394877.1 N-acetyldiaminopimelate deacetylase -
  JZ789_RS11235 (JZ789_11145) dapD 2251601..2252299 (-) 699 WP_170244757.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase -
  JZ789_RS11240 (JZ789_11150) - 2252375..2253115 (-) 741 WP_024387356.1 metallophosphoesterase -
  JZ789_RS11245 (JZ789_11155) - 2253277..2254533 (+) 1257 WP_226316920.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50002.51 Da        Isoelectric Point: 6.1911

>NTDB_id=547977 JZ789_RS11105 WP_004298358.1 2230119..2231489(-) (radA) [Streptococcus suis strain GX69]
MTIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVISVTTIGEVLQKVFNL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=547977 JZ789_RS11105 WP_004298358.1 2230119..2231489(-) (radA) [Streptococcus suis strain GX69]
ATGACCATCGCTAAGAAAAAAACAACCTTTGTCTGTCAATCCTGCGAGTACCACTCGCCCAAGTATCTGGGCCGTTGCCC
CAACTGTGGCTCCTGGTCTAGCTTTGTCGAGGAAGTGGAAGTCGCTGAAGTCAAGAACGAGCGGGTCAGTCTGACAGGTG
AGAAGACCCGTCCTATGAAGCTCAATGAAGTGTCGTCCATTCAAGTGGCCCGCACCAAGACCAATATGGAAGAGTTTAAC
CGTGTCCTTGGTGGCGGCGTGGTGCCGGGCAGTCTGGTCCTGATTGGAGGCGATCCAGGGATTGGCAAATCGACCTTGCT
CCTGCAAGTATCGACCCAACTTTCGACTATTGGCACCGTCCTCTATGTGTCGGGGGAAGAGTCTGCCCAGCAGATTAAGT
TGCGAGCGGAGCGTTTGGGCGACATTGACAGCGAGTTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACTGAG
ATTGAGAAAATCAAGCCAGATTTCCTGATTATCGACTCTATCCAGACCATTATGAGCCCTGACATTTCTAGCGTGCAAGG
TTCTGTCAGTCAGGTCCGTGAAGTGACCAATGAGCTTATGCAGATTGCCAAGACCAACAATATCGCAACCTTTATCGTCG
GCCACATGACCAAGGAAGGCACCCTGGCTGGACCGCGGACCTTGGAGCACATGGTAGACACCGTTCTCTATTTTGAGGGC
GAGCGTCAACACACCTTCCGTATCTTGAGGGCGGTCAAAAATCGCTTTGGCTCCACCAACGAAATCGGTATTTTTGAAAT
GCAGTCGCAGGGCTTGGTCGAAGTTCTCAATCCAAGTGAGGTCTTTCTGGAAGAGCGTCTGGACGGAGCGACTGGCTCGG
CTATTGTCGTGACCATGGAGGGCACCCGCCCTATCCTTGCCGAAGTGCAGGCTCTGGTGACCCCGACCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGCTTGGATTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCCGGTCTGCT
CCTCCAAAACCAAGATGCCTACCTTAAGTCAGCAGGCGGTGTCAAACTGGATGAGCCAGCTATTGACCTAGCGGTCGCAG
TTGCCCTTGCCTCCAGTTACAAGGACAAGCCAACCAACCCACAAGAGTGCTTTATAGGCGAGATTGGCCTGACAGGGGAA
ATCCGCCGCGTCAATCGGATTGAACAACGGATTAACGAAGCCGCCAAATTGGGCTTTACCAAGGTCTATGCCCCAAAAAA
TTCCCTGACAGGTATCAAGGTGCCCAAGGAAATCACCGTTATCAGCGTGACCACCATTGGCGAAGTCTTGCAGAAAGTAT
TCAACTTATGA

Domains

Predicted by InterproScan.

Subunit ChlI of Mg-chelatase (ChlI)

(363-427)

Rubredoxin metal binding domain (Zn_ribbon_LapB)

(10-37)

AAA domain (AAA_25)

(64-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UJP8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radA Streptococcus mitis NCTC 12261

91.15

99.123

0.904
  radA Streptococcus pneumoniae D39

90.929

99.123

0.901
  radA Streptococcus pneumoniae R6

90.929

99.123

0.901
  radA Streptococcus pneumoniae Rx1

90.929

99.123

0.901
  radA Streptococcus pneumoniae TIGR4

90.929

99.123

0.901
  radA Streptococcus mitis SK321

90.708

99.123

0.899
  radA Bacillus subtilis subsp. subtilis str. 168

62.472

99.342

0.621