Detailed information NTG0547965

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: JZ789_RS08915
• Genome accession: NZ_CP071806
• Coordinates: 1773856..1774905 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain GX69
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1768856..1779905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZ789_RS08895 (JZ789_08810)	nadE	1769465..1770289 (+)	825	WP_024413453.1	ammonia-dependent NAD(+) synthetase	-
JZ789_RS08900 (JZ789_08815)	-	1771382..1771909 (-)	528	WP_002942846.1	VanZ family protein	-
JZ789_RS08905 (JZ789_08820)	rlmN	1771906..1773018 (-)	1113	WP_029174969.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
JZ789_RS08910 (JZ789_08825)	-	1773027..1773668 (-)	642	WP_024382386.1	YutD-like domain-containing protein	-
JZ789_RS08915 (JZ789_08830)	sepM	1773856..1774905 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
JZ789_RS08920 (JZ789_08835)	coaD	1774892..1775380 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
JZ789_RS08925 (JZ789_08840)	rsmD	1775370..1775909 (-)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
JZ789_RS08930 (JZ789_08845)	-	1776208..1776930 (-)	723	WP_029174971.1	hypothetical protein	-
JZ789_RS08935 (JZ789_08850)	-	1776987..1777373 (-)	387	WP_087013575.1	rhodanese-like domain-containing protein	-
JZ789_RS08940 (JZ789_08855)	-	1777373..1777591 (-)	219	WP_004194736.1	YqgQ family protein	-
JZ789_RS08945 (JZ789_08860)	-	1777899..1778501 (-)	603	WP_029174973.1	response regulator transcription factor	-
JZ789_RS08950 (JZ789_08865)	-	1778498..1779592 (-)	1095	WP_029174974.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=547965 JZ789_RS08915 WP_012775295.1 1773856..1774905(-) (sepM) [Streptococcus suis strain GX69]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=547965 JZ789_RS08915 WP_012775295.1 1773856..1774905(-) (sepM) [Streptococcus suis strain GX69]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605