Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   LQK05_RS10530 Genome accession   NZ_CP088157
Coordinates   2091756..2092463 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain 199     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2086756..2097463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LQK05_RS10475 (LQK05_10475) - 2087505..2087768 (-) 264 WP_001205732.1 hypothetical protein -
  LQK05_RS10480 (LQK05_10480) - 2087777..2088037 (-) 261 WP_000291488.1 DUF1108 family protein -
  LQK05_RS10485 (LQK05_10485) - 2088130..2088291 (-) 162 WP_000066020.1 DUF1270 domain-containing protein -
  LQK05_RS10490 (LQK05_10490) - 2088288..2088608 (-) 321 WP_001120197.1 DUF771 domain-containing protein -
  LQK05_RS10495 (LQK05_10495) - 2088667..2089299 (+) 633 WP_000275058.1 hypothetical protein -
  LQK05_RS10500 (LQK05_10500) - 2089314..2089454 (-) 141 WP_000939496.1 hypothetical protein -
  LQK05_RS10505 (LQK05_10505) - 2089485..2089682 (-) 198 WP_001148861.1 hypothetical protein -
  LQK05_RS10510 (LQK05_10510) - 2089698..2090453 (-) 756 WP_217654524.1 phage antirepressor KilAC domain-containing protein -
  LQK05_RS10515 (LQK05_10515) - 2090510..2091049 (+) 540 WP_000351243.1 hypothetical protein -
  LQK05_RS10520 (LQK05_10520) - 2091073..2091333 (-) 261 WP_000435341.1 transcriptional regulator -
  LQK05_RS10525 (LQK05_10525) - 2091346..2091585 (-) 240 WP_000548576.1 helix-turn-helix transcriptional regulator -
  LQK05_RS10530 (LQK05_10530) irvR 2091756..2092463 (+) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  LQK05_RS10535 (LQK05_10535) - 2092475..2092621 (+) 147 WP_001049401.1 hypothetical protein -
  LQK05_RS10540 (LQK05_10540) - 2092618..2092803 (+) 186 WP_000109192.1 hypothetical protein -
  LQK05_RS10545 (LQK05_10545) - 2093003..2093185 (+) 183 WP_000705240.1 hypothetical protein -
  LQK05_RS10550 (LQK05_10550) - 2093263..2093976 (+) 714 WP_001549185.1 type II toxin-antitoxin system PemK/MazF family toxin -
  LQK05_RS10555 (LQK05_10555) - 2094168..2095205 (+) 1038 WP_000857185.1 site-specific integrase -
  LQK05_RS10560 (LQK05_10560) sph 2095256..2096086 (+) 831 Protein_2050 sphingomyelin phosphodiesterase -
  LQK05_RS10565 (LQK05_10565) lukG 2096324..2097340 (-) 1017 WP_000595401.1 bi-component leukocidin LukGH subunit G -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=547419 LQK05_RS10530 WP_000094093.1 2091756..2092463(+) (irvR) [Staphylococcus aureus strain 199]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=547419 LQK05_RS10530 WP_000094093.1 2091756..2092463(+) (irvR) [Staphylococcus aureus strain 199]
ATGAGTTCATTTTCTTCGAATCTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTAAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTGTCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374