Detailed information NTG0547279

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: J3S98_RS03015
• Genome accession: NZ_CP071729
• Coordinates: 621700..622731 (+)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain FM-YL11
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 616700..627731

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J3S98_RS02990 (J3S98_02990)	-	617246..617740 (-)	495	WP_021164846.1	RNA polymerase sigma factor	-
J3S98_RS02995 (J3S98_02995)	lmrP	617928..619154 (+)	1227	Protein_569	multidrug efflux MFS transporter LmrP	-
J3S98_RS03000 (J3S98_03000)	-	619238..620458 (+)	1221	WP_021164847.1	MFS transporter	-
J3S98_RS03005 (J3S98_03005)	rsmD	620629..621168 (+)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
J3S98_RS03010 (J3S98_03010)	coaD	621216..621716 (+)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
J3S98_RS03015 (J3S98_03015)	sepM	621700..622731 (+)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
J3S98_RS03020 (J3S98_03020)	-	623050..623163 (+)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
J3S98_RS03025 (J3S98_03025)	kwcM	623231..624550 (+)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
J3S98_RS03030 (J3S98_03030)	-	624657..625547 (-)	891	WP_081146373.1	IS982 family transposase	-
J3S98_RS03035 (J3S98_03035)	-	625835..626044 (+)	210	WP_011677212.1	hypothetical protein	-
J3S98_RS03040 (J3S98_03040)	-	626031..626528 (+)	498	WP_011677211.1	nitroreductase family protein	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=547279 J3S98_RS03015 WP_011677213.1 621700..622731(+) (sepM) [Lactococcus cremoris strain FM-YL11]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=547279 J3S98_RS03015 WP_011677213.1 621700..622731(+) (sepM) [Lactococcus cremoris strain FM-YL11]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49