Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   J1N58_RS02695 Genome accession   NZ_CP071697
Coordinates   543760..545988 (-) Length   742 a.a.
NCBI ID   WP_099780174.1    Uniprot ID   -
Organism   Streptococcus suis strain 1112S     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 538760..550988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS02675 (J1N58_02675) - 539326..539766 (+) 441 WP_099806722.1 GNAT family N-acetyltransferase -
  J1N58_RS02680 (J1N58_02680) ileS 539777..542566 (+) 2790 WP_099876351.1 isoleucine--tRNA ligase -
  J1N58_RS02685 (J1N58_02685) - 542750..543058 (-) 309 WP_002938710.1 DUF1827 family protein -
  J1N58_RS02690 (J1N58_02690) - 543113..543574 (-) 462 WP_002938708.1 NUDIX hydrolase -
  J1N58_RS02695 (J1N58_02695) clpE 543760..545988 (-) 2229 WP_099780174.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  J1N58_RS02700 (J1N58_02700) - 546212..546442 (+) 231 WP_002938704.1 DUF1797 family protein -
  J1N58_RS02705 (J1N58_02705) - 546568..547257 (+) 690 WP_002938702.1 amino acid ABC transporter permease -
  J1N58_RS02710 (J1N58_02710) - 547250..547984 (+) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  J1N58_RS02715 (J1N58_02715) - 548218..549066 (+) 849 WP_024375752.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  J1N58_RS02720 (J1N58_02720) - 549307..549459 (+) 153 WP_099870668.1 YSIRK-type signal peptide-containing protein -
  J1N58_RS02725 (J1N58_02725) - 549419..550003 (+) 585 WP_099870665.1 hypothetical protein -
  J1N58_RS02730 (J1N58_02730) - 550000..550731 (+) 732 WP_099870662.1 hypothetical protein -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82566.93 Da        Isoelectric Point: 5.2782

>NTDB_id=547041 J1N58_RS02695 WP_099780174.1 543760..545988(-) (clpE) [Streptococcus suis strain 1112S]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=547041 J1N58_RS02695 WP_099780174.1 543760..545988(-) (clpE) [Streptococcus suis strain 1112S]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGCATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCCATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAGG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCAGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTAAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGATATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGTTATG
TAGGCTACGAGGAAGCCGGTCAGCTAACTGAAAAAGTCCGCCGCAATCCTTACTCTCTCATCCTCTTGGATGAGGTAGAA
AAAGCCCACCCTGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGGCGGACTGT
CAGCTTCAAAGATACTATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTGGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.493

100

0.838
  clpE Streptococcus pneumoniae D39

82.493

100

0.838
  clpE Streptococcus pneumoniae R6

82.493

100

0.838
  clpE Streptococcus pneumoniae TIGR4

82.493

100

0.838
  clpE Streptococcus mutans UA159

82.51

100

0.833
  clpC Lactococcus lactis subsp. cremoris KW2

77.793

97.709

0.76
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396