Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   H020_RS0106115 Genome accession   NZ_AKVY01000001
Coordinates   1178020..1179309 (-) Length   429 a.a.
NCBI ID   WP_000522333.1    Uniprot ID   A0A0H2UQF6
Organism   Streptococcus pneumoniae TIGR4     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1173020..1184309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0106100 - 1173433..1175598 (+) 2166 WP_000726272.1 ABC transporter substrate-binding protein/permease -
  H020_RS0106105 - 1175598..1176338 (+) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -
  H020_RS0106110 zwf 1176487..1177974 (+) 1488 WP_000096161.1 glucose-6-phosphate dehydrogenase -
  H020_RS0106115 pilA 1178020..1179309 (-) 1290 WP_000522333.1 signal recognition particle-docking protein FtsY Machinery gene
  H020_RS0106120 - 1179313..1180131 (-) 819 WP_000763464.1 Cof-type HAD-IIB family hydrolase -
  H020_RS0106125 - 1180131..1180925 (-) 795 WP_000153039.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 47802.78 Da        Isoelectric Point: 4.1189

>NTDB_id=54692 H020_RS0106115 WP_000522333.1 1178020..1179309(-) (pilA) [Streptococcus pneumoniae TIGR4]
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVS
QEEIEELPNSEELPEEEKLEHEGTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTT
SIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQ
NKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPV
KLIGFGEKIDDIGEFNSENFMKGLLEGLI

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=54692 H020_RS0106115 WP_000522333.1 1178020..1179309(-) (pilA) [Streptococcus pneumoniae TIGR4]
ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTAAAAGAAGCTCTGGAAAATCT
TGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTTGAGGAAGTTTCTCAGGAAGAAGCAGAGGTTGAAATTGTTG
AACAAGCTGTGTTCCAAGAAGAGGAAATCCAAGACACAGTTGAAGAAAGTCAGGATTCAGAGCCAGCTGTAGGGGTTTCT
CAAGAAGAAATAGAAGAATTACCAAACTCAGAAGAATTACCAGAGGAAGAGAAGCTTGAGCACGAAGGAACTGTAGAAGA
AAATAATTCTGAAGTGCTTGAACCAGAAGCTCCTCAAACAGAAGAAACTGTTCAGGAAAAATATGACCGCAGTCTTAAGA
AAACTCGCACAGGTTTCGGTGCCCGCTTGAATGCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAA
CTGGAAGAACTGCTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAGGAACTACGTTACGAAGCCAA
GCTTGAAAATGCCAAGAAACCTGATGTACTTCGTCGTGTCATCATTGAGAAATTGGTTGAGCTTTATGAAAAGGATGGTA
GCTACGATGAAAGCATCCACTTCCAAGATAACTTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACT
TCTATCGGAAAACTAGCCCACCGCTACAAACAAGCTGGTAAGAAGGTCATGCTGGTTGCAGCAGATACCTTCCGTGCGGG
TGCAGTAGCTCAGCTAGCTGAATGGGGCCGACGAGTAGATGTTCCAGTAGTAACTGGACCTGAAAAAGCTGATCCAGCCA
GCGTGGTCTTTGATGGTATGGAACGTGCCGTGACTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAA
AATAAGGATAACCTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTGCCAGAAGCACCACATGAAAC
CTTCTTGGCACTTGATGCATCAACAGGTCAAAATGCCCTAGTACAGGCCAAAGAATTTTCGAAAATCACACCTTTAACGG
GAATTGTTTTGACTAAGATTGATGGAACTGCTCGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTA
AAATTGATTGGTTTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTTATGAAAGGTCTCTTGGAAGG
TTTAATCTAA

Domains

Predicted by InterProScan.

SRP54-type protein, GTPase domain (SRP54)

(226-425)

SRP54-type protein, helical bundle domain (SRP54_N)

(139-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UQF6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

35.616

100

0.364

Multiple sequence alignment