Detailed information NTG0546548

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LO769_RS11560
• Genome accession: NZ_CP087600
• Coordinates: 2276174..2278696 (-)
• Length: 840 a.a.
• NCBI ID: WP_153927553.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain IBB109
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2271174..2283696

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LO769_RS11540 (LO769_11535)	ruvB	2271431..2272432 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LO769_RS11545 (LO769_11540)	ruvA	2272559..2273152 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LO769_RS11550 (LO769_11545)	hexB	2273265..2275235 (-)	1971	WP_252172383.1	DNA mismatch repair endonuclease MutL	Machinery gene
LO769_RS11555 (LO769_11550)	-	2275364..2276059 (-)	696	WP_003131997.1	hypothetical protein	-
LO769_RS11560 (LO769_11555)	hexA	2276174..2278696 (-)	2523	WP_153927553.1	DNA mismatch repair protein MutS	Machinery gene
LO769_RS11565 (LO769_11560)	-	2278890..2279237 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
LO769_RS11570 (LO769_11565)	-	2279453..2280334 (-)	882	WP_003132001.1	NAD(P)-dependent oxidoreductase	-
LO769_RS11575 (LO769_11570)	-	2280376..2280582 (-)	207	WP_003132002.1	hypothetical protein	-
LO769_RS11585 (LO769_11580)	-	2280877..2281254 (-)	378	WP_003132003.1	DUF1634 domain-containing protein	-
LO769_RS11590 (LO769_11585)	-	2281254..2282105 (-)	852	WP_010906392.1	sulfite exporter TauE/SafE family protein	-
LO769_RS11595 (LO769_11590)	-	2282291..2282470 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94249.22 Da
• Isoelectric Point: 4.6787

>NTDB_id=546548 LO769_RS11560 WP_153927553.1 2276174..2278696(-) (hexA) [Lactococcus lactis subsp. lactis strain IBB109]
MAERISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMDLRAETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALVHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=546548 LO769_RS11560 WP_153927553.1 2276174..2278696(-) (hexA) [Lactococcus lactis subsp. lactis strain IBB109]
ATGGCTGAAAGAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGCGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTG
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCGGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCCTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTATGTTAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGCCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTCCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCTAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTGCGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGCTGAATAGTGTTCCTGAACATTTTTATCGTAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGACCTTCGGGCTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGAGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAAACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGTTCATCTTGATAATGTCCATGTTGCTACTTTGGAACAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGACCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (254-544)

• MutS domain II (MutS_II) (124-237)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain V (MutS_V) (598-784)

• MutS domain I (MutS_I) (7-116)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.336	100	0.646
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386