Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPAKL86_RS04535 Genome accession   NC_019563
Coordinates   925285..927069 (+) Length   594 a.a.
NCBI ID   WP_015087255.1    Uniprot ID   -
Organism   Helicobacter pylori Aklavik86     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 920285..932069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPAKL86_RS04510 (HPAKL86_04445) - 920961..922697 (-) 1737 WP_015087250.1 nickel-dependent hydrogenase large subunit -
  HPAKL86_RS04515 (HPAKL86_04450) - 922714..923868 (-) 1155 WP_015087251.1 hydrogenase 1 small subunit -
  HPAKL86_RS04520 (HPAKL86_04455) - 924028..924612 (+) 585 WP_015087252.1 NAD(P)H-dependent oxidoreductase -
  HPAKL86_RS04525 (HPAKL86_04460) - 924652..924831 (-) 180 WP_041200277.1 hypothetical protein -
  HPAKL86_RS04530 (HPAKL86_04465) - 924823..925284 (+) 462 WP_015087254.1 hypothetical protein -
  HPAKL86_RS04535 (HPAKL86_04470) uvrC 925285..927069 (+) 1785 WP_015087255.1 excinuclease ABC subunit UvrC Machinery gene
  HPAKL86_RS04540 (HPAKL86_04475) - 927080..928345 (+) 1266 WP_015087256.1 homoserine dehydrogenase -
  HPAKL86_RS04545 (HPAKL86_04480) - 928346..928690 (+) 345 WP_001211711.1 YraN family protein -
  HPAKL86_RS04550 (HPAKL86_04485) trxA 928779..929099 (+) 321 WP_000020205.1 thioredoxin -
  HPAKL86_RS04555 (HPAKL86_04490) trxB 929105..930040 (+) 936 WP_015087257.1 thioredoxin-disulfide reductase -
  HPAKL86_RS04560 (HPAKL86_04495) - 930207..931031 (+) 825 WP_015087258.1 glycosyltransferase family 25 protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68785.16 Da        Isoelectric Point: 9.8211

>NTDB_id=54594 HPAKL86_RS04535 WP_015087255.1 925285..927069(+) (uvrC) [Helicobacter pylori Aklavik86]
MADLLSSLKNLSHNSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTNFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=54594 HPAKL86_RS04535 WP_015087255.1 925285..927069(+) (uvrC) [Helicobacter pylori Aklavik86]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAATAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACCAATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTTACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAGATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATTTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGCATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTACGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment