Detailed information NTG0545791

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: J2N82_RS04590
• Genome accession: NZ_CP071505
• Coordinates: 921156..922202 (+)
• Length: 348 a.a.
• NCBI ID: WP_053025471.1
• Uniprot ID: -
• Organism: Staphylococcus haemolyticus strain 12b
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 916156..927202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J2N82_RS04565 (J2N82_04565)	map	917033..917785 (+)	753	WP_053025476.1	type I methionyl aminopeptidase	-
J2N82_RS11940	-	918037..918174 (-)	138	WP_245154753.1	hypothetical protein	-
J2N82_RS11945	-	918319..918756 (-)	438	Protein_909	SDR family NAD(P)-dependent oxidoreductase	-
J2N82_RS04575 (J2N82_04575)	-	918828..919833 (-)	1006	Protein_910	HoxN/HupN/NixA family nickel/cobalt transporter	-
J2N82_RS04580 (J2N82_04580)	-	920047..920433 (+)	387	WP_053025474.1	hypothetical protein	-
J2N82_RS04585 (J2N82_04585)	liaF	920458..921159 (+)	702	WP_053025472.1	cell wall-active antibiotics response protein LiaF	-
J2N82_RS04590 (J2N82_04590)	vraS	921156..922202 (+)	1047	WP_053025471.1	sensor histidine kinase	Regulator
J2N82_RS04595 (J2N82_04595)	vraR	922192..922821 (+)	630	WP_053025469.1	two-component system response regulator VraR	Regulator
J2N82_RS04600 (J2N82_04600)	-	922884..924095 (-)	1212	WP_053025467.1	YihY/virulence factor BrkB family protein	-
J2N82_RS04605 (J2N82_04605)	-	924294..924578 (-)	285	WP_053025464.1	YtxH domain-containing protein	-
J2N82_RS04610 (J2N82_04610)	-	924584..925048 (-)	465	WP_207323844.1	low molecular weight protein-tyrosine-phosphatase	-
J2N82_RS04615 (J2N82_04615)	-	925190..925399 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
J2N82_RS04620 (J2N82_04620)	-	925413..926660 (+)	1248	WP_053025460.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40180.57 Da
• Isoelectric Point: 5.8508

>NTDB_id=545791 J2N82_RS04590 WP_053025471.1 921156..922202(+) (vraS) [Staphylococcus haemolyticus strain 12b]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=545791 J2N82_RS04590 WP_053025471.1 921156..922202(+) (vraS) [Staphylococcus haemolyticus strain 12b]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTACTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATTGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCA
CAAATTGAACATGCCATTGAAGGAGAAACAGTAGGTATTAATGATCAAAATATTGAGCTTTATAACGAAACCATAGACCT
TTATCAAACATTAGTTCCGCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGGATGAACGACAGAGATTAGCTCGCGAGTTACACGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCAATAAAAGAAACAAAGTTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAGTCTCAACTTGAAATGCGCGCATTATTACTTCATTTAAGACCTTTAGGTCTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTGCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCAAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGACAATGGTAAAG
GATTCAATGTTGACGAGAAATTAGAGCAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTATCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCGTTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.931	99.713	0.917