Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   JZY07_RS02595 Genome accession   NZ_CP071305
Coordinates   492702..494933 (-) Length   743 a.a.
NCBI ID   WP_024399535.1    Uniprot ID   A0A9Q5BXR2
Organism   Streptococcus suis strain SC183     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 487702..499933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZY07_RS02575 (JZY07_02575) - 488214..488657 (+) 444 WP_024411798.1 GNAT family N-acetyltransferase -
  JZY07_RS02580 (JZY07_02580) ileS 488668..491457 (+) 2790 WP_024411797.1 isoleucine--tRNA ligase -
  JZY07_RS02585 (JZY07_02585) - 491693..492001 (-) 309 WP_002938710.1 DUF1827 family protein -
  JZY07_RS02590 (JZY07_02590) - 492056..492517 (-) 462 WP_024399534.1 NUDIX hydrolase -
  JZY07_RS02595 (JZY07_02595) clpE 492702..494933 (-) 2232 WP_024399535.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  JZY07_RS02600 (JZY07_02600) - 495156..495386 (+) 231 WP_002938704.1 DUF1797 family protein -
  JZY07_RS02605 (JZY07_02605) - 495512..496201 (+) 690 WP_002938702.1 amino acid ABC transporter permease -
  JZY07_RS02610 (JZY07_02610) - 496194..496928 (+) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  JZY07_RS02615 (JZY07_02615) - 497058..497906 (+) 849 WP_024399536.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  JZY07_RS02620 (JZY07_02620) - 499314..499613 (+) 300 WP_014735557.1 hypothetical protein -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 82659.97 Da        Isoelectric Point: 5.3418

>NTDB_id=544852 JZY07_RS02595 WP_024399535.1 492702..494933(-) (clpE) [Streptococcus suis strain SC183]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQ
KATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKISKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEV
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFD
GIIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPA
EKDLHAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=544852 JZY07_RS02595 WP_024399535.1 492702..494933(-) (clpE) [Streptococcus suis strain SC183]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAGTTCTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACA
ACCAAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTC
GCGATCAAGAAATTACACGTGTCATCGAAATTCTCAACCGTCGTACAAAAAATAACCCTGTTCTTATCGGTGAGCCTGGA
GTAGGTAAAACAGCGGTTGTTGAAGGCTTAGCTCAAAAAATTGTCGATGGCGATGTGCCACATAAATTACGAGACAAGGA
AGTCATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGTTCTGCAGGC
GATGGCAACATGGATGCTGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCT
CAACGAATACCGTATTATCGAAAAAGATGCCGCCCTAGAGCGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCG
AAGAAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCAGCTATC
GAAGCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGC
TGGTTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAAGAAATTGACCAACGCCTAATTGATGCCGAAAATCGTA
AAGCACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAA
AAGGCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAGAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATAT
CCCAGTTGGTGATTTAAAAGAAAAAGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGAC
AAGATGAAGCAGTTGACAAGATATCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCAATTGGA
TCCTTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGC
GGACAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCT
ATGTAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTT
GAAAAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGAC
AGTCAGCTTCAAAGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTG
CGGCTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGAC
GGCATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACG
CCTTTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGA
TGGGAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCA
GAAAAAGACCTACATGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)

AAA lid domain (AAA_lid_9)

(292-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.493

100

0.837
  clpE Streptococcus pneumoniae D39

82.493

100

0.837
  clpE Streptococcus pneumoniae R6

82.493

100

0.837
  clpE Streptococcus pneumoniae TIGR4

82.493

100

0.837
  clpE Streptococcus mutans UA159

81.842

100

0.825
  clpC Lactococcus lactis subsp. cremoris KW2

77.41

97.712

0.756
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.483

0.459
  clpC Streptococcus thermophilus LMD-9

48.408

84.522

0.409
  clpC Streptococcus mutans UA159

48.718

83.984

0.409
  clpC Streptococcus thermophilus LMG 18311

48.089

84.522

0.406
  clpC Streptococcus pneumoniae TIGR4

48

84.118

0.404
  clpC Streptococcus pneumoniae Rx1

48

84.118

0.404
  clpC Streptococcus pneumoniae D39

48

84.118

0.404
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.975

84.522

0.397