Detailed information NTG0544826

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: J0J35_RS10415
• Genome accession: NZ_CP071301
• Coordinates: 2107575..2110025 (+)
• Length: 816 a.a.
• NCBI ID: WP_029345874.1
• Uniprot ID: A0AAJ2IUJ5
• Organism: Lactococcus sp. LG606
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2102575..2115025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J35_RS10390 (J0J35_10390)	-	2103496..2104008 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
J0J35_RS10395 (J0J35_10395)	rpoE	2104134..2104694 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
J0J35_RS10400 (J0J35_10400)	mltG	2104800..2106515 (+)	1716	WP_019294152.1	endolytic transglycosylase MltG	-
J0J35_RS10405 (J0J35_10405)	greA	2106540..2107013 (+)	474	WP_019292667.1	transcription elongation factor GreA	-
J0J35_RS10410 (J0J35_10410)	-	2107133..2107585 (+)	453	WP_019292666.1	CtsR family transcriptional regulator	-
J0J35_RS10415 (J0J35_10415)	clpC	2107575..2110025 (+)	2451	WP_029345874.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
J0J35_RS10420 (J0J35_10420)	hpf	2110147..2110704 (+)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
J0J35_RS10425 (J0J35_10425)	pflB	2110952..2113285 (+)	2334	WP_019292664.1	formate C-acetyltransferase	-
J0J35_RS10430 (J0J35_10430)	coaE	2113515..2114120 (+)	606	WP_019294150.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91176.46 Da
• Isoelectric Point: 6.0555

>NTDB_id=544826 J0J35_RS10415 WP_029345874.1 2107575..2110025(+) (clpC) [Lactococcus sp. LG606]
MKFNEKDFTPQVIKVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQDINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEEETVAILQGLKEKFEAYHTVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELRLQKAVVALDIVEAQGIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYPAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=544826 J0J35_RS10415 WP_029345874.1 2107575..2110025(+) (clpC) [Lactococcus sp. LG606]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTCATAAAAGTGCTTGAGAAGTCTGTCGACTATGCGCACAAGTTTAA
CTACGCTTGGGTTGAAAGCTCGCACTTATTGGCTGCCTTGGCTGAGGTCCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAAATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGTCCAAGAGTGGAAACGATTATTGAGCAAGCACGAGCACTGGCTCAAAATAATGATAAAAACCGCATCGGGAC
CGAGCATCTCTTATATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAGACATCAATATCG
TTAACCTCCGCAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAGCGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACCTGTCGGGGAAAGTGTCCGAAACAACGACAACGCCTACTTTAGACACGGTATCAACAGATTTGACAAAAGCAGC
CCGTGAAGGCAAGCTTGATCCCATGATTGGAAGAGAGCGTGAAGTTGAACGTCTTATCCACATTTTGAGCCGTCGAACAA
AAAATAATCCCGTTCTTGTTGGTGAGCCAGGTGTTGGTAAGTCAGCGATTATTGAAGGTTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGCCGCATTATGGCTTTAAATATGGCGATGGTCGTAGCGGGGACAAAATTCCG
TGGTGAATTTGAAGATCGTTTGACGGCTATTGTTGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACCATTATTGGTGCTGGTGGCGGCATGGACTCGGTCAACGATGCCTCAAACATTTTAAAACCAGCATTAGCACGG
GGCGAGTTCCAACTCATTGGTGCTACCACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCCCTAGAACGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAGAGGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAGG
CTTACCATACAGTCAAATTTGAAGAAGGGGCTTTGGAGCGTGCTGTCAGCTTGAGTAATCGCTATATGCCTAGTCGTCGT
CTCCCAGACAAAGCTATTGATCTTCTTGATGAAGCAGCAGCCAAAGTTAAAATCACGAGTAAAACAAATTATACCAAGTT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAACTGAGATTACAAAAAGCAGTTGTTGCTCTTGATATTGTTGAAGCGC
AAGGGATTGAAAAAGATATTGAAAAATTAACGCACAAGATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTG
GAGGAAAGCGATGTTTATGCTGTCGTTTCTAACCTTACAGGAATCCCACTCCAACAGATGACGAAGACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTTGGACAGGAAGAAGCGATTTCTGCTGTTTCTCGTGCCATTA
GACGTGCACGTTCAGGGATTGCCGATACGAGACGTCCTTTGGGCTCATTTATGTTCCTTGGTCCGACAGGAGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGCAGTGAAGAAAATATGATTCGTGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCTGGATATGTAGGTTACGATGAAGGTGGGCAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTCGAAAAGGCCCACCCTGATATTTTCAATATCATGTTA
CAAATTTTGGATGATGGTTTCGTTACAGATACCAAAGGACGTAAAGTTGATTTCAGAAATACGATCATCATTATGACATC
TAACTTGGGTGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACGGATTATCCAGCTA
TGAAAGCAAGAATCATGGAAGAGCTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACTATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCGCGTTTGAAAGATCAAAA
TATCAAAGTAAAATTTACACCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAATACGGTGCCCGCCCAT
TGCGTAAAGCTCTGCAACGTGAGGTTGAAGACACGCTCAGTGAACAATTGCTTGCCGGCGAAATTCATCCAGGGGATACG
ATTTCGATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.92	99.877	0.708
clpC	Streptococcus thermophilus LMG 18311	49.879	100	0.506
clpC	Streptococcus thermophilus LMD-9	49.879	100	0.506
clpC	Streptococcus pneumoniae TIGR4	49.274	100	0.499
clpC	Streptococcus pneumoniae Rx1	49.153	100	0.498
clpC	Streptococcus pneumoniae D39	49.153	100	0.498
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.564	98.162	0.477
clpE	Streptococcus mutans UA159	46.719	78.431	0.366