Detailed information NTG0544808

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: J0J35_RS08110
• Genome accession: NZ_CP071301
• Coordinates: 1650374..1651417 (-)
• Length: 347 a.a.
• NCBI ID: WP_206916591.1
• Uniprot ID: -
• Organism: Lactococcus sp. LG606
• Function: processing of CSP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1644302..1653878	1650374..1651417	within	0

Gene organization within MGE regions

Location: 1644302..1653878

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J35_RS08090 (J0J35_08090)	tsf	1644302..1645330 (-)	1029	WP_003133160.1	translation elongation factor Ts	-
J0J35_RS08095 (J0J35_08095)	rpsB	1645407..1646180 (-)	774	WP_003133158.1	30S ribosomal protein S2	-
J0J35_RS08100 (J0J35_08100)	-	1646453..1647493 (+)	1041	WP_019291938.1	lactonase family protein	-
J0J35_RS08105 (J0J35_08105)	adhE	1647649..1650342 (+)	2694	WP_206916590.1	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	-
J0J35_RS08110 (J0J35_08110)	sepM	1650374..1651417 (-)	1044	WP_206916591.1	SepM family pheromone-processing serine protease	Regulator
J0J35_RS08115 (J0J35_08115)	coaD	1651407..1651904 (-)	498	WP_206916593.1	pantetheine-phosphate adenylyltransferase	-
J0J35_RS08120 (J0J35_08120)	rsmD	1651894..1652433 (-)	540	WP_019293304.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
J0J35_RS08125 (J0J35_08125)	-	1652532..1653878 (-)	1347	WP_003133148.1	glucose-6-phosphate isomerase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 37802.12 Da
• Isoelectric Point: 7.4075

>NTDB_id=544808 J0J35_RS08110 WP_206916591.1 1650374..1651417(-) (sepM) [Lactococcus sp. LG606]
MKNEKIKKHKKLKLFFAIALPLLIVVGLFFPLPYYIEQPGGTIPVNQMVDVAGKKDEHKGNFYLTTVEMVRANAASMLYS
KSNSFATVVSSEEMTGGMTNQQFDLVNQFYMQTAQNTAIYQAFKLAGKPYEMKYQGVYVLSITEDSTFKNDLQLSDTITA
VNGHTFKSSTEMIDYVSQQKVGDSVTIKYTRVDGSNHEATGKYIKLSNGKTGIGIGLVDHTQVVTDPKVKIDAGSIGGPS
AGMMFTLEIYSQITGKDLRQGREIAGTGTINEDGSIGQIGGVDKKVATASNAGAKIFLCPDETEEQTKASGTTNNYTEAL
AAAKKLNTDMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1044 bp

>NTDB_id=544808 J0J35_RS08110 WP_206916591.1 1650374..1651417(-) (sepM) [Lactococcus sp. LG606]
ATGAAAAATGAAAAAATAAAAAAGCATAAAAAACTAAAGCTATTCTTTGCCATCGCGCTACCGCTTCTTATTGTAGTGGG
TTTATTCTTCCCCTTACCTTACTATATCGAGCAGCCAGGAGGAACCATTCCAGTTAACCAAATGGTTGATGTTGCAGGGA
AAAAAGACGAACATAAAGGCAACTTTTATTTAACGACAGTTGAAATGGTTCGCGCCAATGCAGCAAGTATGCTTTATTCC
AAGTCGAACTCTTTTGCCACTGTTGTGAGTAGTGAAGAGATGACGGGTGGAATGACCAATCAGCAATTTGACTTGGTCAA
CCAGTTTTATATGCAGACAGCGCAAAACACGGCTATTTATCAGGCCTTTAAGTTGGCAGGGAAACCTTATGAGATGAAGT
ATCAAGGTGTTTATGTTTTGAGCATCACTGAGGATTCAACCTTTAAAAATGACTTACAACTTTCAGATACGATAACGGCA
GTTAATGGACATACTTTCAAATCTTCAACTGAGATGATTGATTATGTATCGCAACAAAAAGTTGGGGATAGCGTTACCAT
CAAATATACACGTGTGGATGGCAGTAATCATGAAGCCACAGGTAAGTACATTAAGTTGAGTAATGGTAAAACAGGGATTG
GTATTGGTTTAGTAGATCATACCCAGGTTGTGACAGACCCTAAAGTTAAAATCGATGCTGGAAGTATTGGCGGGCCAAGT
GCTGGTATGATGTTTACCTTGGAAATATATAGCCAAATCACAGGCAAAGATTTACGTCAAGGACGCGAAATTGCAGGTAC
TGGAACGATCAATGAGGATGGCAGCATCGGGCAAATAGGTGGCGTTGATAAAAAAGTTGCTACAGCAAGTAATGCGGGCG
CAAAAATTTTCCTTTGCCCAGATGAAACGGAAGAACAGACAAAGGCTTCTGGTACAACAAATAACTACACAGAAGCGCTT
GCGGCAGCTAAAAAGTTGAATACAGATATGAAAATTGTACCTGTAAAGACGATTCAAGATGCGCTAGATTATCTCGAAAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-308)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	49.28	100	0.493