Detailed information NTG0544759

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: JZX84_RS02370
• Genome accession: NZ_CP071300
• Coordinates: 439940..441430 (+)
• Length: 496 a.a.
• NCBI ID: WP_019293246.1
• Uniprot ID: A0AAJ2ML94
• Organism: Lactococcus sp. LG592
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 434940..446430

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZX84_RS02345 (JZX84_02345)	pfkB	435088..436014 (+)	927	WP_165719430.1	1-phosphofructokinase	-
JZX84_RS02350 (JZX84_02350)	-	436029..437933 (+)	1905	WP_019293248.1	fructose-specific PTS transporter subunit EIIC	-
JZX84_RS02355 (JZX84_02355)	-	438045..438287 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
JZX84_RS02360 (JZX84_02360)	-	438504..439055 (+)	552	WP_206888295.1	DUF177 domain-containing protein	-
JZX84_RS02365 (JZX84_02365)	covR	439157..439852 (+)	696	WP_019292077.1	response regulator transcription factor	Regulator
JZX84_RS02370 (JZX84_02370)	covS	439940..441430 (+)	1491	WP_019293246.1	HAMP domain-containing histidine kinase	Regulator
JZX84_RS02375 (JZX84_02375)	-	441826..443397 (+)	1572	WP_019293245.1	ABC transporter permease subunit	-
JZX84_RS02380 (JZX84_02380)	-	443398..444135 (+)	738	WP_019292074.1	amino acid ABC transporter ATP-binding protein	-
JZX84_RS02385 (JZX84_02385)	murD	444275..445636 (+)	1362	WP_165719432.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56888.98 Da
• Isoelectric Point: 5.2995

>NTDB_id=544759 JZX84_RS02370 WP_019293246.1 439940..441430(+) (covS) [Lactococcus sp. LG592]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=544759 JZX84_RS02370 WP_019293246.1 439940..441430(+) (covS) [Lactococcus sp. LG592]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGACATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACAACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56