Detailed information NTG0544671

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: J0J36_RS02185
• Genome accession: NZ_CP071293
• Coordinates: 453640..455130 (+)
• Length: 496 a.a.
• NCBI ID: WP_019293246.1
• Uniprot ID: A0AAJ2ML94
• Organism: Lactococcus sp. LG1074
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 448640..460130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J36_RS02160 (J0J36_02160)	pfkB	448788..449714 (+)	927	WP_153924558.1	1-phosphofructokinase	-
J0J36_RS02165 (J0J36_02165)	-	449729..451633 (+)	1905	WP_019292079.1	fructose-specific PTS transporter subunit EIIC	-
J0J36_RS02170 (J0J36_02170)	-	451745..451987 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
J0J36_RS02175 (J0J36_02175)	-	452204..452755 (+)	552	WP_153924561.1	DUF177 domain-containing protein	-
J0J36_RS02180 (J0J36_02180)	covR	452857..453552 (+)	696	WP_019292077.1	response regulator transcription factor	Regulator
J0J36_RS02185 (J0J36_02185)	covS	453640..455130 (+)	1491	WP_019293246.1	HAMP domain-containing histidine kinase	Regulator
J0J36_RS02190 (J0J36_02190)	-	455526..457097 (+)	1572	WP_019292075.1	ABC transporter permease subunit	-
J0J36_RS02195 (J0J36_02195)	-	457098..457835 (+)	738	WP_019292074.1	amino acid ABC transporter ATP-binding protein	-
J0J36_RS02200 (J0J36_02200)	murD	457975..459336 (+)	1362	WP_019292073.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56888.98 Da
• Isoelectric Point: 5.2995

>NTDB_id=544671 J0J36_RS02185 WP_019293246.1 453640..455130(+) (covS) [Lactococcus sp. LG1074]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=544671 J0J36_RS02185 WP_019293246.1 453640..455130(+) (covS) [Lactococcus sp. LG1074]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGATATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACGACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56