Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SCAZ3_RS04040 Genome accession   NZ_AIDX01000001
Coordinates   888202..890184 (-) Length   660 a.a.
NCBI ID   WP_039994902.1    Uniprot ID   -
Organism   Streptococcus canis FSL Z3-227     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 883202..895184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCAZ3_RS04015 (SCAZ3_11095) cinA 884047..885318 (-) 1272 WP_003045727.1 competence/damage-inducible protein A Machinery gene
  SCAZ3_RS12390 - 885435..885593 (-) 159 WP_223824822.1 VOC family protein -
  SCAZ3_RS04025 (SCAZ3_11105) - 885791..886363 (-) 573 WP_003045731.1 DNA-3-methyladenine glycosylase I -
  SCAZ3_RS04030 (SCAZ3_11110) ruvA 886373..886969 (-) 597 WP_003045733.1 Holliday junction branch migration protein RuvA Machinery gene
  SCAZ3_RS04035 (SCAZ3_11115) - 886953..888191 (-) 1239 WP_003045734.1 MDR family MFS transporter -
  SCAZ3_RS04040 (SCAZ3_11120) hexB 888202..890184 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL Machinery gene
  SCAZ3_RS04045 (SCAZ3_11125) - 890279..891430 (-) 1152 WP_003045739.1 tyrosine-type recombinase/integrase -
  SCAZ3_RS04050 (SCAZ3_11130) dinD 891676..892530 (-) 855 WP_003045741.1 DNA damage-inducible protein D -
  SCAZ3_RS04065 (SCAZ3_11145) - 893561..894145 (-) 585 WP_003045746.1 TMEM175 family protein -
  SCAZ3_RS04070 (SCAZ3_11150) - 894210..894698 (-) 489 WP_003045748.1 prolyl-tRNA synthetase associated domain-containing protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74407.98 Da        Isoelectric Point: 5.7465

>NTDB_id=54325 SCAZ3_RS04040 WP_039994902.1 888202..890184(-) (hexB) [Streptococcus canis FSL Z3-227]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITIEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAIHGSILVATGGKIETLEPISTPIGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIAIQLDPYLADVNVHPTKQEVRISKERELMALISA
AISESLREQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVAEKMPETDFHYGDVDNCVKVEK
TESLPHSEEDTGPSSVKHASRPQDSLVNPDHPDFDLKNKQKLSQMLDRLENEEKSAFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMTLLNEVGIFLEVYGHNTFILREHPIWMKEE
EIESGVYEMCDMLLLTNEVSVKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=54325 SCAZ3_RS04040 WP_039994902.1 888202..890184(-) (hexB) [Streptococcus canis FSL Z3-227]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATCGCAGCTGGTGAGGTTGTAGAAAGACCAGCAAGTGT
TGTCAAGGAGTTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCATTGAAATTGAAGAGTCTGGTCTTAAAA
TGATACAGATTACAGACAATGGTGAAGGGATGTCACATGAAGACCTACCCTTGAGTTTGCGTCGTCATGCCACCAGTAAA
ATTAAAAGTCAGAGTGACCTTTTTCGAATTAGGACGCTTGGATTTCGAGGAGAAGCTTTACCGTCGGTTGCCTCCATTAG
TAAAATCACGATAAAAACTGCAACAAAAGAAGCTATACATGGCTCTATTCTCGTTGCTACGGGTGGGAAAATTGAGACGC
TTGAACCAATCTCAACACCTATTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACTCCTGCCCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAATCGGTTGAGTTTGGCTCACCCAGAAGTTGCTTT
TACACTGATTAGTGATGGTCGTCAATTAACTCAGACCTCAGGGACTGGCGATTTGCGCCAAGCTATTGCTGGTATTTACG
GCTTGAATACTGCGAAGAAAATGATTGCTATCTCTAATGCTGATCTGGATTTTGAAGTGTCTGGATATGTCAGTTTACCA
GAGTTGACACGTGCTAATCGAAACTATATGACAATTTTAATCAATGGACGCTACATTAAAAACTTCTTGCTCAATCGAGC
TATCTTAGATGGTTATGGTTCTAAATTGATGGTTGGACGTTTTCCGATTGTTGTGATTGCTATTCAGCTTGATCCTTACT
TAGCTGATGTCAATGTCCACCCCACAAAGCAAGAGGTTCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATCAGTGCA
GCTATTTCTGAAAGCCTTAGGGAACAAGACTTAATTCCAGATGCACTTGAAAATTTAGCCAAATCAAGCACACGACATTT
TTCCAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTACTATGATCCGCAAAAGAATGACTTTTTTGTCA
AAGAATCGGCTGTCGCGGAAAAAATGCCTGAAACTGATTTTCATTACGGCGATGTTGACAACTGTGTAAAGGTTGAAAAG
ACAGAGTCGCTACCTCACTCAGAAGAAGACACAGGACCTTCTTCAGTAAAGCATGCTAGCCGTCCCCAAGATAGTTTAGT
GAATCCTGATCATCCTGACTTTGACTTAAAAAATAAACAAAAGTTATCTCAAATGTTGGATCGCTTGGAAAATGAAGAAA
AATCAGCATTTCCTGAATTAGATTATTTTGGTCAGATGCATGGGACTTATCTTTTTGCTCAAGGCAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATATGAATATTATCGTGATAAGATTGGCGATGTTGACAGTAGTTT
ACAGCAGTTGTTAGTGCCTTACTTATTTGAGTTTTCTGGTTCGGATTTCATTAATTTACAGGAAAAAATGACACTTCTAA
ATGAAGTCGGTATCTTTCTGGAAGTTTATGGGCACAATACTTTCATTCTGAGGGAACACCCTATCTGGATGAAAGAAGAA
GAGATTGAATCTGGTGTCTATGAAATGTGTGATATGTTACTTTTGACAAATGAGGTATCTGTCAAAACTTATCGAGCAGA
GTTAGCGATTATGATGAGCTGTAAACGGTCTATTAAAGCTAATCACAGTTTAGATGATTATTCAGCAAGGAATCTTTTGC
TGCAATTAGCGCAATGCCAAAATCCTTATAACTGTCCTCATGGCAGACCCGTTTTGATTAACTTTAGCAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCACACTAGTCTACGAGAATTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.477

100

0.688

Multiple sequence alignment