Detailed information NTG0054306

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SDSE_RS14780
• Genome accession: NC_019042
• Coordinates: 838284..840383 (-)
• Length: 699 a.a.
• NCBI ID: WP_015057518.1
• Uniprot ID: A0A9X8T363
• Organism: Streptococcus dysgalactiae subsp. equisimilis AC-2713
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	840656..841518	838284..840383	flank	273

Gene organization within MGE regions

Location: 838284..841518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDSE_RS14780 (S_dysgal_equisimilis_AC2713_887)	clpC	838284..840383 (-)	2100	WP_015057518.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SDSE_RS21405	-	840656..841518 (-)	863	Protein_786	IS982 family transposase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77399.04 Da
• Isoelectric Point: 4.8590

>NTDB_id=54306 SDSE_RS14780 WP_015057518.1 838284..840383(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MTNYYDKDTFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGSEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGHQEDENTDQPTIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISDD
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide

• Length: 2100 bp

>NTDB_id=54306 SDSE_RS14780 WP_015057518.1 838284..840383(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGACAAATTATTATGACAAAGATACTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAGACTGGAC
GTCTGAGCGATAAAGGTAGTGAACAACCTACATCCCAAGGTCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTTTTCTTTGATGAAATTCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGCGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAATGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATGCTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCCGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGACCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACACGAATTGAAGAATTGCAAAAACAAATGGACAACCATAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGATATTGCAGAATCCGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGGACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTCGGTAAGACAGAGTTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACTGCTGTGTCCAAGTTAATCGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGAGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTGGATGATGGCCGATTAACAGATGGTCAGGGAAATACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGCATCAAGAAGATGAAAATACTGATCAACCTACTATTATGGACCGTAT
TGCACCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACCATAGCTAAAAAAGGAATCAGCTTAGCTATCTCTGATGAT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACTTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-679)

• AAA lid domain (AAA_lid_9) (259-353)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.391	100	0.481
clpE	Streptococcus mutans UA159	46.544	100	0.472
clpE	Streptococcus pneumoniae Rx1	48.447	92.132	0.446
clpE	Streptococcus pneumoniae D39	48.447	92.132	0.446
clpE	Streptococcus pneumoniae R6	48.447	92.132	0.446
clpE	Streptococcus pneumoniae TIGR4	48.367	91.989	0.445
clpC	Bacillus subtilis subsp. subtilis str. 168	44.341	92.275	0.409
clpC	Streptococcus pneumoniae Rx1	40.943	97.139	0.398
clpC	Streptococcus pneumoniae D39	40.943	97.139	0.398
clpC	Streptococcus pneumoniae TIGR4	40.795	97.139	0.396
clpC	Streptococcus thermophilus LMG 18311	43.065	88.698	0.382
clpC	Streptococcus thermophilus LMD-9	43.065	88.698	0.382
clpC	Streptococcus mutans UA159	42.903	88.698	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.165	88.555	0.373