Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JYA70_RS13225 Genome accession   NZ_CP071102
Coordinates   2683203..2683919 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain CI/BAC/25/13/W     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2678203..2688919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYA70_RS13205 (JYA70_002640) - 2679295..2680245 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  JYA70_RS13210 (JYA70_002641) - 2680394..2681878 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  JYA70_RS13215 (JYA70_002642) - 2681875..2682834 (+) 960 WP_001253309.1 carbohydrate kinase -
  JYA70_RS13220 (JYA70_002643) - 2683022..2683131 (-) 110 Protein_2575 hypothetical protein -
  JYA70_RS13225 (JYA70_002644) agrA 2683203..2683919 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  JYA70_RS13230 (JYA70_002645) - 2683938..2685221 (-) 1284 WP_000447893.1 sensor histidine kinase -
  JYA70_RS13235 (JYA70_002646) - 2685251..2685394 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  JYA70_RS13240 (JYA70_002647) - 2685397..2685960 (-) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  JYA70_RS13605 hld 2686250..2686330 (+) 81 WP_000046022.1 delta-hemolysin -
  JYA70_RS13250 (JYA70_002649) - 2686930..2687715 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  JYA70_RS13255 (JYA70_002650) - 2688076..2688702 (-) 627 WP_000522376.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=542873 JYA70_RS13225 WP_000688498.1 2683203..2683919(-) (agrA) [Staphylococcus aureus strain CI/BAC/25/13/W]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=542873 JYA70_RS13225 WP_000688498.1 2683203..2683919(-) (agrA) [Staphylococcus aureus strain CI/BAC/25/13/W]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996