Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JYA46_RS13575 Genome accession   NZ_CP070991
Coordinates   2728161..2728877 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CBS2016-05     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2723161..2733877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYA46_RS13555 (JYA46_002711) - 2724254..2725204 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  JYA46_RS13560 (JYA46_002712) - 2725354..2726838 (+) 1485 WP_072491855.1 sucrose-6-phosphate hydrolase -
  JYA46_RS13565 (JYA46_002713) - 2726835..2727794 (+) 960 WP_001253302.1 carbohydrate kinase -
  JYA46_RS13570 (JYA46_002714) - 2727982..2728089 (-) 108 WP_072491856.1 hypothetical protein -
  JYA46_RS13575 (JYA46_002715) agrA 2728161..2728877 (-) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  JYA46_RS13580 (JYA46_002716) - 2728896..2730188 (-) 1293 WP_210994212.1 GHKL domain-containing protein -
  JYA46_RS13585 (JYA46_002717) - 2730213..2730353 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  JYA46_RS13590 (JYA46_002718) agrB 2730350..2730919 (-) 570 WP_001105714.1 accessory gene regulator AgrB -
  JYA46_RS13595 (JYA46_002719) hld 2731210..2731290 (+) 81 WP_000046022.1 delta-hemolysin -
  JYA46_RS13600 (JYA46_002720) - 2731889..2732674 (-) 786 WP_072491857.1 carbon-nitrogen family hydrolase -
  JYA46_RS13605 (JYA46_002721) - 2732983..2733609 (-) 627 WP_070043934.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=541996 JYA46_RS13575 WP_000688492.1 2728161..2728877(-) (agrA) [Staphylococcus aureus strain CBS2016-05]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=541996 JYA46_RS13575 WP_000688492.1 2728161..2728877(-) (agrA) [Staphylococcus aureus strain CBS2016-05]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCC
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1