Detailed information NTG0541952

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JYH18_RS13115
• Genome accession: NZ_CP070986
• Coordinates: 2673315..2674202 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain WBG8287
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2668315..2679202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JYH18_RS13085 (JYH18_13085)	-	2668334..2668426 (+)	93	WP_010956583.1	hypothetical protein	-
JYH18_RS13090 (JYH18_13090)	-	2668534..2669031 (-)	498	WP_001065268.1	glutathione peroxidase	-
JYH18_RS13095 (JYH18_13095)	-	2669041..2669301 (-)	261	WP_001791974.1	hypothetical protein	-
JYH18_RS13100 (JYH18_13100)	-	2669683..2669796 (-)	114	Protein_2552	hypothetical protein	-
JYH18_RS13105 (JYH18_13105)	-	2670455..2672455 (-)	2001	WP_000776740.1	ABC transporter permease	-
JYH18_RS13110 (JYH18_13110)	-	2672452..2673207 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JYH18_RS13115 (JYH18_13115)	braS	2673315..2674202 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JYH18_RS13120 (JYH18_13120)	braR	2674213..2674878 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JYH18_RS13125 (JYH18_13125)	-	2674904..2675104 (-)	201	WP_000604727.1	hypothetical protein	-
JYH18_RS13130 (JYH18_13130)	-	2675302..2676726 (+)	1425	WP_000953748.1	alkaline phosphatase	-
JYH18_RS13135 (JYH18_13135)	-	2676796..2676906 (+)	111	WP_001791296.1	hypothetical protein	-
JYH18_RS13140 (JYH18_13140)	-	2677009..2677464 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JYH18_RS13145 (JYH18_13145)	-	2677709..2678470 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=541952 JYH18_RS13115 WP_000143417.1 2673315..2674202(-) (braS) [Staphylococcus aureus strain WBG8287]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=541952 JYH18_RS13115 WP_000143417.1 2673315..2674202(-) (braS) [Staphylococcus aureus strain WBG8287]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99