Detailed information NTG0541946

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JYH18_RS09370
• Genome accession: NZ_CP070986
• Coordinates: 1946137..1947180 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain WBG8287
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1941137..1952180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JYH18_RS09340 (JYH18_09340)	-	1941565..1942821 (-)	1257	WP_078055712.1	aminopeptidase	-
JYH18_RS09345 (JYH18_09345)	-	1942824..1943024 (-)	201	WP_000180460.1	DUF1128 family protein	-
JYH18_RS09350 (JYH18_09350)	-	1943171..1943635 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JYH18_RS09355 (JYH18_09355)	-	1943642..1943917 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JYH18_RS09360 (JYH18_09360)	-	1944195..1945406 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
JYH18_RS09365 (JYH18_09365)	vraR	1945518..1946147 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
JYH18_RS09370 (JYH18_09370)	vraS	1946137..1947180 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JYH18_RS09375 (JYH18_09375)	liaF	1947177..1947878 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JYH18_RS09380 (JYH18_09380)	-	1947893..1948279 (-)	387	WP_001110179.1	hypothetical protein	-
JYH18_RS09385 (JYH18_09385)	map	1948496..1949254 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JYH18_RS09390 (JYH18_09390)	-	1949785..1950771 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
JYH18_RS09395 (JYH18_09395)	-	1951261..1951674 (-)	414	WP_001837236.1	hypothetical protein	-
JYH18_RS09400 (JYH18_09400)	-	1951703..1951814 (-)	112	Protein_1820	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=541946 JYH18_RS09370 WP_001017131.1 1946137..1947180(-) (vraS) [Staphylococcus aureus strain WBG8287]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=541946 JYH18_RS09370 WP_001017131.1 1946137..1947180(-) (vraS) [Staphylococcus aureus strain WBG8287]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1