Detailed information NTG0541074

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: JWR96_RS08455
• Genome accession: NZ_CP070856
• Coordinates: 1719200..1721446 (-)
• Length: 748 a.a.
• NCBI ID: WP_043736111.1
• Uniprot ID: A0AAX4A440
• Organism: Lactococcus cremoris strain GR0507
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1714200..1726446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JWR96_RS08435 (JWR96_08435)	-	1715865..1716320 (-)	456	WP_043736105.1	RNA pyrophosphohydrolase	-
JWR96_RS08440 (JWR96_08440)	def	1716475..1717110 (+)	636	WP_043736107.1	peptide deformylase	-
JWR96_RS08445 (JWR96_08445)	gap	1717335..1718348 (-)	1014	WP_011834565.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
JWR96_RS08450 (JWR96_08450)	-	1718574..1719044 (+)	471	WP_043736109.1	Rrf2 family transcriptional regulator	-
JWR96_RS08455 (JWR96_08455)	clpC	1719200..1721446 (-)	2247	WP_043736111.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
JWR96_RS08460 (JWR96_08460)	-	1721492..1721836 (-)	345	WP_043736113.1	hypothetical protein	-
JWR96_RS08465 (JWR96_08465)	-	1722146..1723525 (-)	1380	WP_043736114.1	MFS transporter	-
JWR96_RS08470 (JWR96_08470)	-	1723682..1724425 (-)	744	WP_043736116.1	MurR/RpiR family transcriptional regulator	-
JWR96_RS08475 (JWR96_08475)	rpoD	1724523..1725866 (-)	1344	WP_011675564.1	RNA polymerase sigma factor RpoD	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83208.02 Da
• Isoelectric Point: 4.7590

>NTDB_id=541074 JWR96_RS08455 WP_043736111.1 1719200..1721446(-) (clpC) [Lactococcus cremoris strain GR0507]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKIEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=541074 JWR96_RS08455 WP_043736111.1 1719200..1721446(-) (clpC) [Lactococcus cremoris strain GR0507]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGACGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGGCGATGTGCCACAAAAACTGCAAAATAAAGAAGTCATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATCCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGAGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCGCGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATTAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCCAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTTGGCTATGAAG
AAGCAGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAATTGAAGCTTCTGTTGGATTTGGTGCAGCTCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTTGACTTAGGATATAATCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (287-386)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	99.733	100	0.997
clpE	Streptococcus mutans UA159	75.894	100	0.766
clpE	Streptococcus pneumoniae Rx1	75.815	98.396	0.746
clpE	Streptococcus pneumoniae D39	75.815	98.396	0.746
clpE	Streptococcus pneumoniae R6	75.815	98.396	0.746
clpE	Streptococcus pneumoniae TIGR4	75.815	98.396	0.746
clpC	Bacillus subtilis subsp. subtilis str. 168	48.664	95.053	0.463
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.023	87.567	0.412
clpC	Streptococcus pneumoniae Rx1	46.955	83.422	0.392
clpC	Streptococcus pneumoniae D39	46.955	83.422	0.392
clpC	Streptococcus pneumoniae TIGR4	46.955	83.422	0.392
clpC	Streptococcus thermophilus LMD-9	46.429	82.353	0.382
clpC	Streptococcus thermophilus LMG 18311	46.266	82.353	0.381
clpC	Streptococcus mutans UA159	45.631	82.62	0.377