Detailed information NTG0541073

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: JWR96_RS08090
• Genome accession: NZ_CP070856
• Coordinates: 1652819..1655269 (-)
• Length: 816 a.a.
• NCBI ID: WP_043736030.1
• Uniprot ID: A0AAX4AHC9
• Organism: Lactococcus cremoris strain GR0507
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1647819..1660269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JWR96_RS08065 (JWR96_08065)	-	1648206..1648775 (+)	570	WP_043736022.1	TetR/AcrR family transcriptional regulator	-
JWR96_RS08070 (JWR96_08070)	-	1648787..1649860 (+)	1074	WP_043736024.1	ABC transporter permease	-
JWR96_RS08075 (JWR96_08075)	-	1649862..1650533 (+)	672	WP_043736026.1	ABC transporter ATP-binding protein	-
JWR96_RS08080 (JWR96_08080)	eno	1650638..1651939 (-)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
JWR96_RS08085 (JWR96_08085)	raiA	1652127..1652684 (-)	558	WP_043736028.1	ribosome-associated translation inhibitor RaiA	-
JWR96_RS08090 (JWR96_08090)	clpC	1652819..1655269 (-)	2451	WP_043736030.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
JWR96_RS08095 (JWR96_08095)	-	1655259..1655714 (-)	456	WP_011834627.1	CtsR family transcriptional regulator	-
JWR96_RS08100 (JWR96_08100)	greA	1655909..1656379 (-)	471	WP_011834626.1	transcription elongation factor GreA	-
JWR96_RS08105 (JWR96_08105)	mltG	1656440..1658080 (-)	1641	WP_043736031.1	endolytic transglycosylase MltG	-
JWR96_RS08110 (JWR96_08110)	rpoE	1658216..1658779 (-)	564	WP_015082149.1	DNA-directed RNA polymerase subunit delta	-
JWR96_RS08115 (JWR96_08115)	-	1658995..1659507 (-)	513	WP_011834623.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90332.71 Da
• Isoelectric Point: 6.6284

>NTDB_id=541073 JWR96_RS08090 WP_043736030.1 1652819..1655269(-) (clpC) [Lactococcus cremoris strain GR0507]
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVSVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=541073 JWR96_RS08090 WP_043736030.1 1652819..1655269(-) (clpC) [Lactococcus cremoris strain GR0507]
ATGAAATTTGAAAATGTAAAATATACACCAACGCTGGACCGAATTTTCGAAAAAGCAGCAGAATATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTTTCTGTAGCTAGCTTTTTGGCAGTTCATAATAATGCAGAAGCAGTAGGAAC
AGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTCTTCAACTTTTGAAGTTACAAAAAATCAACATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGTGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATCGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCCCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGATTTTCAAATGGTTGGGGCAACGACTTATCATGAATACCAAAAATATATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATCTTACAAGGGTTACGAGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCTGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATCGACTTGCTTGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAGCTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAATTTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTTGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGATAACATGATTCGAGTGGATATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGGGCCCCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GTGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCCCATCCAGACGTATTCAATATCATGCTC
CAAATTTTAGACGATGGATTTGTGACAGATACAAAGGGTCGTAAAGTTGATTTTAGAAATACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGGGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATTGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAACAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA lid domain (AAA_lid_9) (357-449)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	95.956	100	0.96
clpC	Streptococcus thermophilus LMD-9	51.023	100	0.52
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus pneumoniae Rx1	49.517	100	0.502
clpC	Streptococcus pneumoniae D39	49.517	100	0.502
clpC	Streptococcus pneumoniae TIGR4	49.396	100	0.501
clpC	Streptococcus mutans UA159	49.038	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	50.249	98.284	0.494
clpE	Streptococcus mutans UA159	46.923	79.657	0.374
clpC	Lactococcus lactis subsp. cremoris KW2	46.626	79.902	0.373
clpE	Streptococcus pneumoniae TIGR4	47.049	76.838	0.362
clpE	Streptococcus pneumoniae Rx1	47.049	76.838	0.362
clpE	Streptococcus pneumoniae D39	47.049	76.838	0.362
clpE	Streptococcus pneumoniae R6	47.049	76.838	0.362