Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   LK447_RS06620 Genome accession   NZ_CP085947
Coordinates   1387289..1388170 (+) Length   293 a.a.
NCBI ID   WP_000481618.1    Uniprot ID   B5Z7C5
Organism   Helicobacter pylori strain FDAARGOS_1563     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1382289..1393170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK447_RS06600 (LK447_06600) - 1383153..1384469 (+) 1317 WP_240448229.1 MATE family efflux transporter -
  LK447_RS06605 (LK447_06605) rny 1384470..1385981 (-) 1512 WP_041201368.1 ribonuclease Y -
  LK447_RS06610 (LK447_06610) - 1385959..1386600 (-) 642 WP_000816537.1 5-formyltetrahydrofolate cyclo-ligase -
  LK447_RS06615 (LK447_06615) - 1386725..1387282 (+) 558 WP_001220421.1 hypothetical protein -
  LK447_RS06620 (LK447_06620) pilA 1387289..1388170 (+) 882 WP_000481618.1 signal recognition particle-docking protein FtsY Machinery gene
  LK447_RS06625 (LK447_06625) - 1388179..1388499 (-) 321 WP_000392889.1 YkgJ family cysteine cluster protein -
  LK447_RS06630 (LK447_06630) - 1388564..1389505 (-) 942 WP_000926363.1 hypothetical protein -
  LK447_RS06635 (LK447_06635) - 1389535..1391086 (-) 1552 Protein_1300 hypothetical protein -
  LK447_RS06640 (LK447_06640) moaA 1391330..1392295 (-) 966 WP_041201319.1 GTP 3',8-cyclase MoaA -
  LK447_RS06645 (LK447_06645) mobA 1392382..1392987 (+) 606 WP_000795289.1 molybdenum cofactor guanylyltransferase MobA -

Sequence

Protein


Download         Length: 293 a.a.        Molecular weight: 32665.96 Da        Isoelectric Point: 7.4169

>NTDB_id=539306 LK447_RS06620 WP_000481618.1 1387289..1388170(+) (pilA) [Helicobacter pylori strain FDAARGOS_1563]
MFNFFKKIVNKIKGEEVKEKKRENIPKEELEEILIGFDIQYDLIENLLKHLGDLVTPKQLEVALLRFVRGESYYDKTRLK
TITTKPLVHLIVGVNGAGKTTTIAKLAKLSLKQHKKALLGAGDTFRAAAVKQLQLWGEKLNIQVISAKEGSDPSSLAYNT
IESAIAKNIDEVFIDTAGRLHNQTNLKNELSKIARTCSKVLKDAPFYKFLILDGTQGSSGLTQAKIFHETLALDGVIMTK
LDGTSKGGAILSVLYELKLPILYLGMGEKEDDLIAFDEERFIEDLVDAVFVEQ

Nucleotide


Download         Length: 882 bp        

>NTDB_id=539306 LK447_RS06620 WP_000481618.1 1387289..1388170(+) (pilA) [Helicobacter pylori strain FDAARGOS_1563]
ATGTTTAATTTTTTTAAAAAAATTGTCAATAAGATTAAGGGCGAAGAGGTTAAAGAAAAAAAGCGTGAAAATATCCCTAA
AGAGGAATTAGAAGAAATTTTGATTGGCTTTGACATCCAATACGATTTGATAGAGAACTTGTTAAAGCATTTAGGCGATT
TGGTTACGCCCAAGCAACTAGAAGTCGCTTTGTTGCGTTTTGTGCGTGGGGAAAGCTATTATGATAAAACCCGCCTAAAA
ACTATCACCACAAAACCCTTAGTGCATTTAATCGTTGGGGTTAATGGGGCGGGCAAAACCACAACGATCGCTAAATTAGC
CAAACTCTCTTTAAAACAGCATAAAAAAGCGCTTTTAGGAGCCGGCGATACCTTTAGAGCGGCCGCAGTCAAACAGCTGC
AATTATGGGGCGAAAAGCTTAACATTCAAGTCATTAGCGCTAAAGAAGGGAGCGATCCAAGCTCTCTAGCTTACAACACC
ATAGAAAGCGCGATCGCTAAAAATATAGATGAAGTTTTTATAGACACCGCTGGGAGGTTACACAACCAGACCAACCTTAA
AAACGAGCTTTCTAAAATCGCGCGCACCTGCTCTAAAGTTTTAAAAGACGCCCCCTTTTATAAATTCCTTATTTTAGACG
GCACGCAAGGGAGTTCTGGTCTCACTCAAGCGAAAATTTTCCATGAGACTTTGGCGTTAGATGGCGTGATTATGACTAAG
CTTGATGGCACTTCTAAAGGCGGAGCGATTTTAAGCGTGCTGTATGAGTTGAAATTACCCATTCTTTATTTAGGAATGGG
CGAAAAAGAAGACGATCTGATCGCTTTTGATGAAGAACGATTTATAGAAGATTTAGTTGATGCGGTGTTTGTGGAACAAT
AA

Domains

Predicted by InterProScan.

SRP54-type protein, GTPase domain (SRP54)

(87-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B5Z7C5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

41.199

91.126

0.375