Detailed information NTG0539124

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JQN76_RS13410
• Genome accession: NZ_CP070305
• Coordinates: 2722980..2724023 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. SM3655
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2717980..2729023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQN76_RS13380 (JQN76_13380)	-	2718402..2719658 (-)	1257	WP_001793428.1	aminopeptidase	-
JQN76_RS13385 (JQN76_13385)	-	2719661..2719861 (-)	201	WP_000180463.1	DUF1128 family protein	-
JQN76_RS13390 (JQN76_13390)	-	2720008..2720472 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JQN76_RS13395 (JQN76_13395)	-	2720479..2720754 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JQN76_RS13400 (JQN76_13400)	-	2721032..2722249 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
JQN76_RS13405 (JQN76_13405)	vraR	2722361..2722990 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
JQN76_RS13410 (JQN76_13410)	vraS	2722980..2724023 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JQN76_RS13415 (JQN76_13415)	liaF	2724020..2724721 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JQN76_RS13420 (JQN76_13420)	-	2724736..2725122 (-)	387	WP_001110179.1	hypothetical protein	-
JQN76_RS13425 (JQN76_13425)	map	2725339..2726097 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
JQN76_RS13430 (JQN76_13430)	-	2726628..2727614 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
JQN76_RS13435 (JQN76_13435)	-	2728045..2728458 (-)	414	WP_001549145.1	hypothetical protein	-
JQN76_RS13440 (JQN76_13440)	-	2728487..2728597 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=539124 JQN76_RS13410 WP_001017131.1 2722980..2724023(-) (vraS) [Staphylococcus sp. SM3655]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=539124 JQN76_RS13410 WP_001017131.1 2722980..2724023(-) (vraS) [Staphylococcus sp. SM3655]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1