Detailed information NTG0538986

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: JRC45_RS14815
• Genome accession: NZ_CP070287
• Coordinates: 2978907..2979536 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain Sample 168
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2964998..2979336	2978907..2979536	flank	-429

Gene organization within MGE regions

Location: 2964998..2979536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JRC45_RS14745 (JRC45_14745)	-	2965061..2967541 (+)	2481	WP_204628614.1	exonuclease	-
JRC45_RS14750 (JRC45_14750)	-	2967608..2967859 (+)	252	WP_000273158.1	DUF4224 domain-containing protein	-
JRC45_RS14755 (JRC45_14755)	-	2967828..2968847 (+)	1020	WP_024227504.1	tyrosine-type recombinase/integrase	-
JRC45_RS14760 (JRC45_14760)	yccA	2969256..2969915 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
JRC45_RS14765 (JRC45_14765)	tusE	2970007..2970336 (+)	330	WP_024164819.1	sulfurtransferase TusE	-
JRC45_RS14770 (JRC45_14770)	yccX	2970333..2970611 (-)	279	WP_000048219.1	acylphosphatase	-
JRC45_RS14775 (JRC45_14775)	rlmI	2970705..2971895 (+)	1191	WP_000116313.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
JRC45_RS14780 (JRC45_14780)	hspQ	2971953..2972270 (+)	318	WP_001295356.1	heat shock protein HspQ	-
JRC45_RS14785 (JRC45_14785)	-	2972315..2972728 (-)	414	WP_098401493.1	CoA-binding protein	-
JRC45_RS14790 (JRC45_14790)	-	2972901..2973563 (+)	663	WP_000847777.1	DUF2057 family protein	-
JRC45_RS14795 (JRC45_14795)	mgsA	2973659..2974117 (+)	459	WP_000424182.1	methylglyoxal synthase	-
JRC45_RS14800 (JRC45_14800)	helD	2974149..2976203 (-)	2055	WP_204629469.1	DNA helicase IV	-
JRC45_RS14805 (JRC45_14805)	-	2976326..2976772 (+)	447	WP_001261228.1	YccF domain-containing protein	-
JRC45_RS14810 (JRC45_14810)	yccS	2976782..2978947 (+)	2166	WP_072244615.1	YccS family putative transporter	-
JRC45_RS14815 (JRC45_14815)	sxy/tfoX	2978907..2979536 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=538986 JRC45_RS14815 WP_000839162.1 2978907..2979536(-) (sxy/tfoX) [Escherichia albertii strain Sample 168]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=538986 JRC45_RS14815 WP_000839162.1 2978907..2979536(-) (sxy/tfoX) [Escherichia albertii strain Sample 168]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTAGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCATCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904