Detailed information NTG0538912

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLUL021_RS11975
• Genome accession: NZ_CP070263
• Coordinates: 2347711..2348739 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis subsp. lactis strain UL021
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2342711..2353739

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUL021_RS11950 (LLUL021_11910)	-	2342997..2343494 (-)	498	WP_003132662.1	nitroreductase family protein	-
LLUL021_RS11955 (LLUL021_11915)	-	2343481..2343690 (-)	210	WP_003132661.1	hypothetical protein	-
LLUL021_RS11960 (LLUL021_11920)	-	2343687..2344514 (-)	828	WP_137016648.1	radical SAM protein	-
LLUL021_RS11965 (LLUL021_11925)	-	2344507..2346630 (-)	2124	WP_137016650.1	radical SAM protein	-
LLUL021_RS11970 (LLUL021_11930)	-	2346733..2347590 (-)	858	WP_003132658.1	Rgg/GadR/MutR family transcriptional regulator	-
LLUL021_RS11975 (LLUL021_11935)	sepM	2347711..2348739 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LLUL021_RS11980 (LLUL021_11940)	coaD	2348726..2349223 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LLUL021_RS11985 (LLUL021_11945)	rsmD	2349271..2349810 (-)	540	WP_003132655.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLUL021_RS11990 (LLUL021_11950)	-	2349981..2351201 (-)	1221	WP_003132654.1	MFS transporter	-
LLUL021_RS11995 (LLUL021_11955)	lmrP	2351285..2352508 (-)	1224	Protein_2335	multidrug efflux MFS transporter LmrP	-
LLUL021_RS12000 (LLUL021_11960)	-	2352696..2353190 (+)	495	WP_012898649.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=538912 LLUL021_RS11975 WP_003132657.1 2347711..2348739(-) (sepM) [Lactococcus lactis subsp. lactis strain UL021]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=538912 LLUL021_RS11975 WP_003132657.1 2347711..2348739(-) (sepM) [Lactococcus lactis subsp. lactis strain UL021]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTGGTGCCTGACTCAGGCACCAAAAAAGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491