Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   LJA35_RS16405 Genome accession   NZ_CP085300
Coordinates   3721852..3722976 (+) Length   374 a.a.
NCBI ID   WP_030404779.1    Uniprot ID   A0A6B3QRH4
Organism   Streptomyces sp. BSE6.1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3716852..3727976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LJA35_RS16395 - 3718023..3719813 (-) 1791 WP_233646018.1 hypothetical protein -
  LJA35_RS16400 radA/sms 3720361..3721770 (+) 1410 WP_102932190.1 DNA repair protein RadA Machinery gene
  LJA35_RS16405 disA 3721852..3722976 (+) 1125 WP_030404779.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  LJA35_RS16410 - 3722996..3723838 (-) 843 WP_233646019.1 hypothetical protein -
  LJA35_RS16415 - 3723997..3724923 (+) 927 WP_125629511.1 A/G-specific adenine glycosylase -
  LJA35_RS16420 - 3725222..3725755 (+) 534 WP_003975479.1 SigE family RNA polymerase sigma factor -
  LJA35_RS16425 - 3725743..3726420 (+) 678 WP_176154385.1 hypothetical protein -
  LJA35_RS16430 cseB 3726544..3727248 (+) 705 WP_233646020.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40084.82 Da        Isoelectric Point: 5.0058

>NTDB_id=538203 LJA35_RS16405 WP_030404779.1 3721852..3722976(+) (disA) [Streptomyces sp. BSE6.1]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=538203 LJA35_RS16405 WP_030404779.1 3721852..3722976(+) (disA) [Streptomyces sp. BSE6.1]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCATCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TGGTGTCGGTTTCGCAGTCGATGCGGCTGATCGCGTTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGACTCGGCGGCG
ATCCTGTCGCGGGCCAATCAGGCACTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCACTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAACGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCCAAGCGCTCCCGTACGGTCGACGA
GGCACTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6B3QRH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.26

96.524

0.447