Detailed information NTG0537558

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: I6K94_RS05500
• Genome accession: NZ_CP069954
• Coordinates: 1242545..1244173 (+)
• Length: 542 a.a.
• NCBI ID: WP_204982858.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain FDAARGOS_1364
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1244695..1256596	1242545..1244173	flank	522
SCCmec	1235789..1244173	1242545..1244173	within	0

Gene organization within MGE regions

Location: 1235789..1256596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K94_RS05475 (I6K94_05475)	-	1235789..1237279 (-)	1491	WP_150868507.1	RNA-binding domain-containing protein	-
I6K94_RS05480 (I6K94_05480)	-	1237678..1238725 (-)	1048	Protein_1096	ACP synthase	-
I6K94_RS05485 (I6K94_05485)	-	1238863..1239153 (+)	291	WP_001036438.1	hypothetical protein	-
I6K94_RS05490 (I6K94_05490)	-	1239153..1240940 (+)	1788	WP_150868230.1	DUF927 domain-containing protein	-
I6K94_RS05495 (I6K94_05495)	ccrA	1241174..1242523 (+)	1350	WP_060649736.1	recombinase family protein	Machinery gene
I6K94_RS05500 (I6K94_05500)	ccrB	1242545..1244173 (+)	1629	WP_204982858.1	recombinase family protein	Machinery gene
I6K94_RS05505 (I6K94_05505)	-	1244695..1245045 (+)	351	WP_001836581.1	SAUGI family uracil-DNA glycosylase inhibitor	-
I6K94_RS05510 (I6K94_05510)	-	1245132..1245443 (+)	312	WP_001631033.1	DUF960 domain-containing protein	-
I6K94_RS05515 (I6K94_05515)	-	1245459..1245962 (+)	504	WP_001631032.1	DUF1643 domain-containing protein	-
I6K94_RS05520 (I6K94_05520)	-	1245977..1246197 (+)	221	Protein_1104	hypothetical protein	-
I6K94_RS05525 (I6K94_05525)	-	1246360..1246770 (+)	411	WP_001631031.1	DUF2871 domain-containing protein	-
I6K94_RS05535 (I6K94_05535)	-	1247442..1247939 (+)	498	WP_001631030.1	GNAT family N-acetyltransferase	-
I6K94_RS05540 (I6K94_05540)	-	1248001..1248217 (+)	217	Protein_1107	IS5/IS1182 family transposase	-
I6K94_RS05545 (I6K94_05545)	-	1248262..1249464 (-)	1203	WP_001631029.1	restriction endonuclease subunit S	-
I6K94_RS05550 (I6K94_05550)	-	1249457..1249600 (-)	144	WP_001631028.1	restriction endonuclease subunit R	-
I6K94_RS05555 (I6K94_05555)	rlmH	1249701..1250180 (-)	480	WP_002458513.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I6K94_RS05560 (I6K94_05560)	-	1251222..1252022 (-)	801	WP_002447628.1	MBL fold metallo-hydrolase	-
I6K94_RS05565 (I6K94_05565)	yycI	1252642..1253433 (-)	792	WP_001831750.1	two-component system regulatory protein YycI	-
I6K94_RS05570 (I6K94_05570)	-	1253434..1254771 (-)	1338	WP_002470548.1	YycH family regulatory protein	-
I6K94_RS05575 (I6K94_05575)	walK	1254764..1256596 (-)	1833	WP_002437327.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62635.88 Da
• Isoelectric Point: 9.9763

>NTDB_id=537558 I6K94_RS05500 WP_204982858.1 1242545..1244173(+) (ccrB) [Staphylococcus epidermidis strain FDAARGOS_1364]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
IYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELIINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMRQILEVVKNDKVIQLVVARVNQKNKVDGASLHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide

• Length: 1629 bp

>NTDB_id=537558 I6K94_RS05500 WP_204982858.1 1242545..1244173(+) (ccrB) [Staphylococcus epidermidis strain FDAARGOS_1364]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATAGATTGTGTTATG
ATCTACAAAACAAACCGATTAGCTCGTAATACATCGGATCTTCTGAAAATCGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATAATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTTGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTGAATCATAAAGGCTATGTCACTAAAA
AAGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCTTGTAGTAATTTTCGCAACAAAGGATCCAAAGTATGTTCGGCGAACAGTGT
AAGAGCCGATGTGATTGAAGATTATGTGATGAGACAAATACTCGAAGTAGTCAAAAATGATAAAGTCATTCAACTCGTTG
TAGCACGTGTCAATCAAAAAAATAAAGTTGATGGTGCCTCACTTCATCACGATATCGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

• Resolvase, N terminal domain (Resolvase) (11-156)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	97.417	100	0.974