Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   I6K93_RS11160 Genome accession   NZ_CP069951
Coordinates   2335374..2336723 (+) Length   449 a.a.
NCBI ID   WP_000815640.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain FDAARGOS_1363     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2330203..2346698 2335374..2336723 within 0


Gene organization within MGE regions


Location: 2330203..2346698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K93_RS11140 (I6K93_11140) - 2330203..2331357 (-) 1155 WP_000912116.1 ATP-binding protein -
  I6K93_RS11145 (I6K93_11145) - 2331812..2332858 (+) 1047 WP_001042023.1 hypothetical protein -
  I6K93_RS11150 (I6K93_11150) - 2333051..2333347 (+) 297 WP_000273823.1 single-stranded DNA-binding protein -
  I6K93_RS11155 (I6K93_11155) - 2333347..2335140 (+) 1794 WP_000079473.1 DUF927 domain-containing protein -
  I6K93_RS11160 (I6K93_11160) ccrA 2335374..2336723 (+) 1350 WP_000815640.1 recombinase family protein Machinery gene
  I6K93_RS11165 (I6K93_11165) ccrB 2336745..2338373 (+) 1629 WP_001186608.1 recombinase family protein Machinery gene
  I6K93_RS11170 (I6K93_11170) - 2338895..2339245 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6K93_RS11175 (I6K93_11175) - 2339332..2339643 (+) 312 WP_000700851.1 DUF960 family protein -
  I6K93_RS11180 (I6K93_11180) - 2339658..2340164 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  I6K93_RS11185 (I6K93_11185) - 2340216..2341811 (+) 1596 Protein_2167 IS1182 family transposase -
  I6K93_RS11190 (I6K93_11190) - 2341908..2343107 (-) 1200 WP_080003806.1 IS110-like element ISSep2 family transposase -
  I6K93_RS11195 (I6K93_11195) - 2343374..2343634 (-) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  I6K93_RS11200 (I6K93_11200) - 2343606..2344592 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  I6K93_RS11205 (I6K93_11205) mecA 2344689..2346698 (+) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52663.34 Da        Isoelectric Point: 9.9639

>NTDB_id=537536 I6K93_RS11160 WP_000815640.1 2335374..2336723(+) (ccrA) [Staphylococcus epidermidis strain FDAARGOS_1363]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=537536 I6K93_RS11160 WP_000815640.1 2335374..2336723(+) (ccrA) [Staphylococcus epidermidis strain FDAARGOS_1363]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.55

100

0.976
  ccrA Staphylococcus aureus COL

75.947

100

0.759