Detailed information NTG0537228

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I6K87_RS00370
• Genome accession: NZ_CP069892
• Coordinates: 66867..69149 (-)
• Length: 760 a.a.
• NCBI ID: WP_204982628.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 61867..74149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS00350 (I6K87_00350)	-	63812..64111 (-)	300	WP_003023675.1	DUF1827 family protein	-
I6K87_RS00355 (I6K87_00355)	-	64175..64624 (-)	450	WP_059220993.1	NUDIX hydrolase	-
I6K87_RS00360 (I6K87_00360)	-	64700..65824 (-)	1125	WP_204982627.1	PTS sugar transporter subunit IIC	-
I6K87_RS00365 (I6K87_00365)	-	66215..66823 (+)	609	WP_003030207.1	GyrI-like domain-containing protein	-
I6K87_RS00370 (I6K87_00370)	clpE	66867..69149 (-)	2283	WP_204982628.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6K87_RS00375 (I6K87_00375)	-	69388..69618 (+)	231	WP_003023686.1	DUF1797 family protein	-
I6K87_RS00380 (I6K87_00380)	-	69783..70259 (+)	477	WP_003030197.1	FeoA family protein	-
I6K87_RS00385 (I6K87_00385)	feoB	70256..72400 (+)	2145	WP_003030196.1	ferrous iron transport protein B	-
I6K87_RS00390 (I6K87_00390)	-	72409..72543 (+)	135	WP_003030194.1	FeoB-associated Cys-rich membrane protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 84743.83 Da
• Isoelectric Point: 4.9167

>NTDB_id=537228 I6K87_RS00370 WP_204982628.1 66867..69149(-) (clpE) [Streptococcus anginosus strain FDAARGOS_1357]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNLGNFQNHQEPQTPP
TQSGGSYGNGGYGSNQGGGARQQTPQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRSRQDVILFIDEIHEIVGAGAAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLVEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEV
EKAHPDVIHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVLGELGNFFSPEFMNRFD
GIIEFKSLDKENLLKIVDLMLEDVNERLATNDIHLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
EKELKAVMTSNGKIVIKSTKKAENEANKEIQTPAADDNAN

Nucleotide

• Length: 2283 bp

>NTDB_id=537228 I6K87_RS00370 WP_204982628.1 66867..69149(-) (clpE) [Streptococcus anginosus strain FDAARGOS_1357]
ATGCTTTGTCAAAACTGTAAAATAAATGAATCAACCATTCACCTTTACACGAATGTGAATGGAAAACAACACCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACAGATCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAACAATC
AAAATAATTTAGACCCTTTTGATGATTTCTTTAGCAATCTAGGGAATTTTCAAAATCATCAAGAACCGCAGACCCCTCCT
ACTCAATCTGGAGGTAGTTACGGCAATGGAGGTTACGGTTCCAATCAAGGTGGGGGTGCACGCCAGCAAACTCCGCAACA
GCCTAAAGGCCTCCTAGAAGAATTTGGTATCAATGTAACCGAATTTGCTCGGCGCGGTGAAATTGACCCTGTCATCGGTC
GTGATGAGGAAATCGTCCGCGTCATTGAAATTCTCAACCGTCGGACGAAGAACAACCCTGTCCTCATAGGAGAGCCCGGT
GTCGGTAAAACAGCTGTTGTAGAAGGCTTGGCCCAGAAGATTGTGGACGGTGATGTTCCACACAAACTCCAAGGAAAAGA
AGTCATCCGTTTAGATGTAGTCAGCCTAGTGCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGGAAGAAATCCGTTCTCGTCAGGATGTGATTTTATTCATTGATGAAATCCATGAAATCGTTGGAGCTGGTGCAGCTGGA
GATGGCAATATGGATGCTGGCAACATCTTAAAACCCGCTCTTGCTCGCGGTGAGCTTCAATTAGTTGGTGCCACAACTCT
CAATGAGTATCGCATTATCGAAAAAGATGCAGCACTGGAACGCCGGATGCAGCCAGTAAAAGTGGATGAACCAACGGTTG
AAGAAACCATTACTATTTTAAAAGGCATTCAAAAAAAATACGAAGACTATCATCACGTTAAATATACAGATGATGCCATT
GAAGCGGCAGCTGTCTTATCCAATCGTTATATCCAAGATCGTTTCTTGCCAGATAAGGCTATTGACTTGCTAGACGAAGC
AGGTTCTAAAATGAATCTGACACTTAATTTTGTTGATCCCAAAGTTATTGATCAACGCTTGGTAGAAGCTGAAAATCTCA
AGGCACAAGCTACTCGTGATGAAGATTTTGAAAAAGCTGCCTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCAGACCAAGATACACCTATTATCAGTGAAAAAACCATTGAGCATATCATTGAGCAAAAAACAAATAT
CCCAGTTGGTGATCTAAAAGAAAAGGAACAATCGCAACTGATTAGTCTAGCTGATGATTTGAAAGCTCATGTCATCGGTC
AAGATGATGCCGTTGATAAAATTGCCAAAGCCATTCGCCGTAATCGTGTCGGGCTTGGCTCTCCTAATCGACCAATTGGT
TCCTTCCTCTTTGTCGGACCAACCGGTGTCGGTAAAACAGAACTTTCTAAACAATTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAAAAACACAGCGTAGCCAAACTCGTTGGAGCACCTCCAGGCT
ATGTTGGCTACGAAGAAGCCGGACAATTGACAGAGCGCGTACGCCGCAATCCTTACTCTCTCATTTTACTTGACGAAGTA
GAAAAAGCGCACCCAGATGTCATACACATGTTCCTGCAAGTTCTTGACGACGGACGTCTGACAGACGGACAAGGGCGCAC
AGTTAGCTTTAAAGATACGATTATCATTATGACTTCAAACGCTGGTACTGGCAAAGTCGAAGCAAATGTTGGCTTTGGAG
CAGCGCGTGAAGGACGGACTAACTCTGTTCTCGGTGAATTAGGCAACTTCTTCAGTCCAGAATTTATGAACCGCTTTGAC
GGTATTATCGAATTCAAGTCCCTTGATAAGGAAAATCTCCTAAAAATCGTAGACTTGATGCTTGAAGATGTCAATGAACG
GCTTGCAACAAATGACATTCACCTCGACGTGACAGACAAAGTCAAAGAAAAATTAGTTAATTTGGGTTACGATCCGAAAA
TGGGAGCTCGTCCGCTCCGTCGGACAATCCAAGATCACATCGAAGACGCCATTACTGATTACTACCTTGAACACCCAAGT
GAAAAAGAACTCAAGGCTGTCATGACAAGCAACGGTAAAATTGTCATCAAATCAACTAAAAAAGCTGAAAATGAAGCCAA
CAAAGAAATCCAAACACCAGCAGCAGATGACAATGCTAATTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (477-640)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (648-722)

• AAA lid domain (AAA_lid_9) (292-389)

• ATPase family associated with various cellular activities (AAA) (AAA) (154-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	87.383	98.026	0.857
clpE	Streptococcus pneumoniae D39	87.383	98.026	0.857
clpE	Streptococcus pneumoniae R6	87.383	98.026	0.857
clpE	Streptococcus pneumoniae TIGR4	87.248	98.026	0.855
clpE	Streptococcus mutans UA159	85.007	98.289	0.836
clpC	Lactococcus lactis subsp. cremoris KW2	76.741	100	0.768
clpC	Bacillus subtilis subsp. subtilis str. 168	50.072	91.711	0.459
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.325	82.5	0.399
clpC	Streptococcus pneumoniae Rx1	48.148	81.711	0.393
clpC	Streptococcus pneumoniae D39	48.148	81.711	0.393
clpC	Streptococcus pneumoniae TIGR4	47.987	81.711	0.392
clpC	Streptococcus mutans UA159	47.115	82.105	0.387
clpC	Streptococcus thermophilus LMG 18311	46.314	82.105	0.38
clpC	Streptococcus thermophilus LMD-9	46.388	81.974	0.38