Detailed information NTG0536806

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JS513_RS13615
• Genome accession: NZ_CP069799
• Coordinates: 2717636..2718523 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 014S_SA
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2712636..2723523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JS513_RS13585 (JS513_13585)	-	2712664..2712747 (+)	84	WP_031797553.1	hypothetical protein	-
JS513_RS13590 (JS513_13590)	-	2712855..2713352 (-)	498	WP_001065271.1	glutathione peroxidase	-
JS513_RS13595 (JS513_13595)	-	2713362..2713622 (-)	261	WP_001789307.1	hypothetical protein	-
JS513_RS13600 (JS513_13600)	-	2714004..2714117 (-)	114	WP_011447078.1	hypothetical protein	-
JS513_RS13605 (JS513_13605)	-	2714776..2716776 (-)	2001	WP_000776751.1	ABC transporter permease	-
JS513_RS13610 (JS513_13610)	-	2716773..2717528 (-)	756	WP_204997642.1	ABC transporter ATP-binding protein	-
JS513_RS13615 (JS513_13615)	braS	2717636..2718523 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JS513_RS13620 (JS513_13620)	braR	2718534..2719199 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JS513_RS13625 (JS513_13625)	-	2719225..2719425 (-)	201	WP_000604727.1	hypothetical protein	-
JS513_RS13630 (JS513_13630)	-	2719623..2721047 (+)	1425	WP_000953734.1	alkaline phosphatase	-
JS513_RS13635 (JS513_13635)	-	2721117..2721227 (+)	111	Protein_2655	hypothetical protein	-
JS513_RS13640 (JS513_13640)	-	2721330..2721785 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JS513_RS13645 (JS513_13645)	-	2722030..2722791 (-)	762	WP_000323453.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=536806 JS513_RS13615 WP_000143419.1 2717636..2718523(-) (braS) [Staphylococcus aureus strain 014S_SA]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=536806 JS513_RS13615 WP_000143419.1 2717636..2718523(-) (braS) [Staphylococcus aureus strain 014S_SA]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997