Detailed information NTG0536801

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JS513_RS09730
• Genome accession: NZ_CP069799
• Coordinates: 1976138..1977181 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 014S_SA
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1971138..1982181

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JS513_RS09700 (JS513_09700)	-	1971560..1972816 (-)	1257	WP_001789555.1	aminopeptidase	-
JS513_RS09705 (JS513_09705)	-	1972819..1973019 (-)	201	WP_000180460.1	DUF1128 family protein	-
JS513_RS09710 (JS513_09710)	-	1973166..1973630 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JS513_RS09715 (JS513_09715)	-	1973637..1973912 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JS513_RS09720 (JS513_09720)	-	1974190..1975407 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
JS513_RS09725 (JS513_09725)	vraR	1975519..1976148 (-)	630	WP_000153531.1	two-component system response regulator VraR	Regulator
JS513_RS09730 (JS513_09730)	vraS	1976138..1977181 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JS513_RS09735 (JS513_09735)	liaF	1977178..1977879 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JS513_RS09740 (JS513_09740)	-	1977894..1978280 (-)	387	WP_001110179.1	hypothetical protein	-
JS513_RS09745 (JS513_09745)	map	1978497..1979255 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JS513_RS09750 (JS513_09750)	-	1979727..1980713 (+)	987	WP_000999720.1	aromatic acid exporter family protein	-
JS513_RS09755 (JS513_09755)	-	1981144..1981557 (-)	414	WP_001566709.1	hypothetical protein	-
JS513_RS09760 (JS513_09760)	-	1981586..1981696 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=536801 JS513_RS09730 WP_001017131.1 1976138..1977181(-) (vraS) [Staphylococcus aureus strain 014S_SA]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=536801 JS513_RS09730 WP_001017131.1 1976138..1977181(-) (vraS) [Staphylococcus aureus strain 014S_SA]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1