Detailed information NTG0535715

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J34_RS11325
• Genome accession: NZ_CP069582
• Coordinates: 2275370..2276413 (+)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain FDAARGOS_1204
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2270370..2281413

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J34_RS11300 (I6J34_11300)	-	2271347..2272072 (+)	726	WP_046100409.1	type 1 glutamine amidotransferase	-
I6J34_RS11305 (I6J34_11305)	-	2272122..2273108 (-)	987	WP_103211659.1	FUSC family protein	-
I6J34_RS11310 (I6J34_11310)	map	2273360..2274127 (+)	768	WP_015900707.1	type I methionyl aminopeptidase	-
I6J34_RS11315 (I6J34_11315)	-	2274261..2274656 (+)	396	WP_015900706.1	hypothetical protein	-
I6J34_RS11320 (I6J34_11320)	liaF	2274672..2275373 (+)	702	WP_046100411.1	cell wall-active antibiotics response protein LiaF	-
I6J34_RS11325 (I6J34_11325)	vraS	2275370..2276413 (+)	1044	WP_015900704.1	sensor histidine kinase	Regulator
I6J34_RS11330 (I6J34_11330)	vraR	2276403..2277032 (+)	630	WP_046100412.1	response regulator transcription factor	Regulator
I6J34_RS11335 (I6J34_11335)	-	2277082..2277660 (-)	579	WP_103211755.1	beta-class carbonic anhydrase	-
I6J34_RS11340 (I6J34_11340)	-	2277870..2278946 (-)	1077	WP_046100413.1	YihY/virulence factor BrkB family protein	-
I6J34_RS11345 (I6J34_11345)	-	2279065..2279361 (-)	297	WP_103211754.1	hypothetical protein	-
I6J34_RS11350 (I6J34_11350)	-	2279369..2279833 (-)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
I6J34_RS11355 (I6J34_11355)	-	2280069..2280275 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=535715 I6J34_RS11325 WP_015900704.1 2275370..2276413(+) (vraS) [Staphylococcus carnosus strain FDAARGOS_1204]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=535715 I6J34_RS11325 WP_015900704.1 2275370..2276413(+) (vraS) [Staphylococcus carnosus strain FDAARGOS_1204]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847