Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   I6J35_RS11480 Genome accession   NZ_CP069567
Coordinates   2301065..2302690 (+) Length   541 a.a.
NCBI ID   WP_204107979.1    Uniprot ID   -
Organism   Staphylococcus condimenti strain FDAARGOS_1205     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2266335..2301043 2301065..2302690 flank 22


Gene organization within MGE regions


Location: 2266335..2302690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J35_RS11345 (I6J35_11345) - 2268108..2268446 (+) 339 WP_065865891.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6J35_RS11350 (I6J35_11350) - 2268542..2268853 (+) 312 WP_053464988.1 DUF960 family protein -
  I6J35_RS11355 (I6J35_11355) - 2268868..2269374 (+) 507 WP_204107961.1 DUF1643 domain-containing protein -
  I6J35_RS11360 (I6J35_11360) - 2269568..2269858 (+) 291 WP_204107962.1 hypothetical protein -
  I6J35_RS11365 (I6J35_11365) - 2269874..2270368 (+) 495 WP_204107963.1 hypothetical protein -
  I6J35_RS11370 (I6J35_11370) - 2270494..2271741 (-) 1248 WP_204107964.1 restriction endonuclease subunit S -
  I6J35_RS11375 (I6J35_11375) - 2271734..2273290 (-) 1557 WP_204107965.1 type I restriction-modification system subunit M -
  I6J35_RS11380 (I6J35_11380) - 2273408..2276200 (-) 2793 WP_204107966.1 type I restriction endonuclease subunit R -
  I6J35_RS11385 (I6J35_11385) - 2276457..2277530 (+) 1074 WP_204107967.1 hypothetical protein -
  I6J35_RS11390 (I6J35_11390) - 2277565..2278314 (+) 750 WP_096808027.1 hypothetical protein -
  I6J35_RS11395 (I6J35_11395) - 2278396..2279334 (+) 939 Protein_2207 DUF1002 domain-containing protein -
  I6J35_RS11400 (I6J35_11400) galU 2279615..2280487 (+) 873 WP_275414408.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  I6J35_RS11405 (I6J35_11405) - 2280586..2281134 (+) 549 WP_204107968.1 DUF6270 domain-containing protein -
  I6J35_RS11410 (I6J35_11410) - 2281131..2281820 (+) 690 WP_204107969.1 hypothetical protein -
  I6J35_RS11415 (I6J35_11415) - 2282035..2282595 (+) 561 WP_204107970.1 DUF6270 domain-containing protein -
  I6J35_RS11420 (I6J35_11420) - 2282607..2283791 (+) 1185 WP_239121898.1 accessory Sec system protein Asp2 -
  I6J35_RS11425 (I6J35_11425) - 2283811..2286324 (+) 2514 WP_204107971.1 glycosyltransferase -
  I6J35_RS11430 (I6J35_11430) - 2286357..2289257 (+) 2901 WP_204107972.1 CDP-glycerol glycerophosphotransferase family protein -
  I6J35_RS11435 (I6J35_11435) - 2289686..2290651 (-) 966 WP_204107973.1 mechanosensitive ion channel -
  I6J35_RS11440 (I6J35_11440) srtA 2290682..2291275 (-) 594 WP_193839861.1 class A sortase SrtA -
  I6J35_RS11445 (I6J35_11445) - 2291384..2293582 (-) 2199 WP_204107974.1 LysM peptidoglycan-binding domain-containing protein -
  I6J35_RS11450 (I6J35_11450) - 2293677..2293892 (-) 216 WP_204107975.1 hypothetical protein -
  I6J35_RS13245 - 2294227..2294796 (-) 570 WP_239121899.1 hypothetical protein -
  I6J35_RS13250 - 2294961..2295419 (-) 459 WP_239121904.1 PD-(D/E)XK nuclease family protein -
  I6J35_RS11460 (I6J35_11460) - 2295848..2297275 (+) 1428 WP_204107976.1 DUF6038 family protein -
  I6J35_RS11465 (I6J35_11465) cch1 2297401..2299191 (+) 1791 WP_204107977.1 cassette chromosome replicative helicase -
  I6J35_RS11470 (I6J35_11470) - 2299259..2299516 (+) 258 WP_070817192.1 hypothetical protein -
  I6J35_RS11475 (I6J35_11475) ccrA 2299694..2301043 (+) 1350 WP_204107978.1 cassette chromosome recombinase CcrA Machinery gene
  I6J35_RS11480 (I6J35_11480) ccrB 2301065..2302690 (+) 1626 WP_204107979.1 cassette chromosome recombinase CcrB Machinery gene

Sequence

Protein


Download         Length: 541 a.a.        Molecular weight: 62098.97 Da        Isoelectric Point: 9.7113

>NTDB_id=535660 I6J35_RS11480 WP_204107979.1 2301065..2302690(+) (ccrB) [Staphylococcus condimenti strain FDAARGOS_1205]
MNEMKKKRIGAYIRVSTERQVEGYSIDGQITQIEQFCQFNGYDLVDIYADRGISGKSMNRPALQRMLQDAKNGKLDCVIV
YKINRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLLLNILASFSEFERNTILENIYTGQHQRALEGYYQGNI
PLGYSNIPDNKKELMINQHEANIVNYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDKPVIAEGKHSPIIGKDLWDKVQARKKQVSKKPQVHGKGTNLLTGIIFCEKCGAAYAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVLKQVVERVNQENQIDVASLNHDVAYKQQQFDE
INTKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITNQINQLKHQQNQEKPSYDTKQIAALLQQIFQNVESMDKAQLKA
LYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNDTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1626 bp        

>NTDB_id=535660 I6J35_RS11480 WP_204107979.1 2301065..2302690(+) (ccrB) [Staphylococcus condimenti strain FDAARGOS_1205]
ATGAATGAAATGAAGAAGAAGAGAATCGGAGCGTACATTCGCGTGTCCACAGAGAGACAAGTGGAAGGTTATAGTATAGA
TGGTCAAATTACACAAATAGAGCAGTTTTGCCAATTTAATGGTTATGACCTCGTTGATATATACGCAGATCGGGGTATTT
CTGGAAAATCTATGAATCGCCCTGCACTACAGCGCATGTTACAAGACGCAAAAAATGGAAAGTTAGACTGTGTGATTGTT
TATAAAATAAATCGTTTAGCACGTAATACTTCTGACTTACTGACAATCGTCGAAGAACTACATCGTCAAAATGTTGAATT
TTTCAGCTTGTCTGAACGCATGGAAGTCAAAAATTCAACAGGTAAATTATTATTAAATATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATACCATTTTAGAGAATATTTACACCGGACAGCATCAAAGAGCCTTAGAAGGCTATTATCAAGGCAATATT
CCTTTAGGATATTCTAATATACCTGATAATAAAAAAGAATTAATGATTAACCAACATGAAGCCAATATTGTGAACTATAT
CTTTGAATCATACGCCAAAGGTCATGGATATCGTAAAATTGCCAATGCACTCAACCATAAAGGATATGTAACTAAGAAAG
GTAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAATCCATTCTATATTGGTAAAATCCAATTCGCGAAATAC
AAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAGCCAGTAATCGCTGAAGGTAAGCACTCCCCTATTATTGG
CAAAGACTTATGGGATAAAGTCCAAGCACGTAAGAAGCAAGTAAGCAAAAAGCCACAGGTACATGGTAAAGGGACAAATC
TGTTAACTGGAATAATTTTCTGCGAAAAATGTGGTGCAGCATATGCAGCTTCAAATACAACCAACACACTCAAAGACGGT
ACTAAAAAACGCATTCGGTATTATTCATGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGTTAG
AGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTCTCAAGCAAGTTGTCG
AACGTGTTAATCAAGAAAATCAAATCGATGTAGCTTCACTTAACCATGATGTTGCTTATAAACAACAACAATTTGATGAA
ATTAACACTAAACTTAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTGAATGACATTACAAATCAAATTAATCAGCTCAAGCACCAACAAAACCAAGAAAAACCATCTT
ACGATACGAAGCAAATCGCTGCCCTATTACAACAAATATTTCAAAACGTAGAATCAATGGATAAAGCACAACTCAAAGCA
TTATACCTTACGGTCATTGATCGTATCGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTCAAACT
CAATAATGAAATTATTAAACAACTTTTCAATGATACCCCACTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTTTGC
CTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(294-359)

Recombinase (Recombinase)

(179-279)

Resolvase, N terminal domain (Resolvase)

(11-154)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

78.044

100

0.782