Detailed information NTG0534942

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J73_RS07200
• Genome accession: NZ_CP069473
• Coordinates: 1511633..1512679 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain FDAARGOS_1243
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1506633..1517679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J73_RS07175 (I6J73_07175)	-	1507774..1508310 (+)	537	WP_001830372.1	hypothetical protein	-
I6J73_RS07180 (I6J73_07180)	-	1508461..1509447 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
I6J73_RS07185 (I6J73_07185)	map	1509621..1510376 (+)	756	WP_001830397.1	type I methionyl aminopeptidase	-
I6J73_RS07190 (I6J73_07190)	-	1510534..1510920 (+)	387	WP_001830382.1	hypothetical protein	-
I6J73_RS07195 (I6J73_07195)	liaF	1510935..1511636 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
I6J73_RS07200 (I6J73_07200)	vraS	1511633..1512679 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
I6J73_RS07205 (I6J73_07205)	vraR	1512669..1513298 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
I6J73_RS07210 (I6J73_07210)	-	1513355..1514533 (-)	1179	WP_021298785.1	YihY/virulence factor BrkB family protein	-
I6J73_RS07215 (I6J73_07215)	-	1514940..1515224 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
I6J73_RS07220 (I6J73_07220)	-	1515232..1515696 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
I6J73_RS07225 (I6J73_07225)	-	1515837..1516052 (+)	216	WP_010959205.1	DUF1128 domain-containing protein	-
I6J73_RS07230 (I6J73_07230)	-	1516054..1517295 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=534942 I6J73_RS07200 WP_001830374.1 1511633..1512679(+) (vraS) [Staphylococcus epidermidis strain FDAARGOS_1243]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=534942 I6J73_RS07200 WP_001830374.1 1511633..1512679(+) (vraS) [Staphylococcus epidermidis strain FDAARGOS_1243]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92