Detailed information NTG0534886

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: I6J76_RS00565
• Genome accession: NZ_CP069470
• Coordinates: 126216..127103 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_1246
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 121216..132103

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J76_RS00535 (I6J76_00535)	-	121948..122709 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
I6J76_RS00540 (I6J76_00540)	-	122954..123409 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
I6J76_RS14615	-	123531..123632 (+)	102	WP_000731972.1	SE2200 family small protein	-
I6J76_RS00550 (I6J76_00550)	-	123692..125116 (-)	1425	WP_000953744.1	alkaline phosphatase	-
I6J76_RS00555 (I6J76_00555)	-	125314..125514 (+)	201	WP_000604728.1	hypothetical protein	-
I6J76_RS00560 (I6J76_00560)	braR	125540..126205 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
I6J76_RS00565 (I6J76_00565)	braS	126216..127103 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
I6J76_RS00570 (I6J76_00570)	-	127211..127966 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
I6J76_RS00575 (I6J76_00575)	-	127963..129963 (+)	2001	WP_000776751.1	ABC transporter permease	-
I6J76_RS00580 (I6J76_00580)	-	130622..130735 (+)	114	WP_001791776.1	hypothetical protein	-
I6J76_RS00585 (I6J76_00585)	-	131117..131377 (+)	261	WP_001789910.1	hypothetical protein	-
I6J76_RS00590 (I6J76_00590)	-	131387..131884 (+)	498	WP_001065268.1	glutathione peroxidase	-
I6J76_RS00595 (I6J76_00595)	-	131992..132084 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=534886 I6J76_RS00565 WP_000143419.1 126216..127103(+) (braS) [Staphylococcus aureus strain FDAARGOS_1246]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=534886 I6J76_RS00565 WP_000143419.1 126216..127103(+) (braS) [Staphylococcus aureus strain FDAARGOS_1246]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997