Detailed information NTG0534529

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: JQM34_RS05565
• Genome accession: NZ_CP069427
• Coordinates: 1194156..1195193 (-)
• Length: 345 a.a.
• NCBI ID: WP_000730772.1
• Uniprot ID: A0A1X1GB13
• Organism: Streptococcus oralis strain SF100
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1189156..1200193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQM34_RS05540 (JQM34_0001130)	-	1190051..1191382 (-)	1332	WP_200370492.1	hemolysin family protein	-
JQM34_RS05545 (JQM34_0001131)	-	1191518..1192341 (-)	824	Protein_1103	DNA/RNA non-specific endonuclease	-
JQM34_RS05550 (JQM34_0001133)	-	1192382..1192576 (-)	195	WP_000739700.1	DNA-directed RNA polymerase subunit beta	-
JQM34_RS05555 (JQM34_0001134)	murA	1192563..1193846 (-)	1284	WP_180833558.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
JQM34_RS05560	-	1193870..1194100 (-)	231	WP_002892633.1	DUF1146 family protein	-
JQM34_RS05565 (JQM34_0001136)	sepM	1194156..1195193 (-)	1038	WP_000730772.1	SepM family pheromone-processing serine protease	Regulator
JQM34_RS05570 (JQM34_0001137)	coaD	1195177..1195665 (-)	489	WP_200370493.1	pantetheine-phosphate adenylyltransferase	-
JQM34_RS05575 (JQM34_0001138)	rsmD	1195655..1196194 (-)	540	WP_002874201.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
JQM34_RS05580 (JQM34_0001139)	asnA	1196259..1197251 (-)	993	WP_000747998.1	aspartate--ammonia ligase	-
JQM34_RS05585 (JQM34_0001140)	-	1197361..1198044 (-)	684	WP_200370494.1	Bax inhibitor-1/YccA family protein	-
JQM34_RS05590 (JQM34_0001141)	-	1198099..1198839 (-)	741	WP_200370495.1	RNA methyltransferase	-
JQM34_RS05595 (JQM34_0001142)	-	1198873..1199151 (+)	279	WP_001174609.1	acylphosphatase	-
JQM34_RS05600 (JQM34_0001143)	yidC	1199229..1200158 (+)	930	WP_049479479.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37539.74 Da
• Isoelectric Point: 5.5304

>NTDB_id=534529 JQM34_RS05565 WP_000730772.1 1194156..1195193(-) (sepM) [Streptococcus oralis strain SF100]
MKKKTRWPLYVILALVLTFLAFVVPLPYYIEVPGGAEDIRRVLKVNETEDTEAGAYQFVTVGIRHATLSHLVYAWLTPFT
DIRSAKETTGGSTDAEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
DSSKDLVDYVNSQQLGDTVKVTYEEDGKVKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVAASRQGANIFFAPDNPVTEEAKKADPNAKSNYETALEAAK
TIKTEMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=534529 JQM34_RS05565 WP_000730772.1 1194156..1195193(-) (sepM) [Streptococcus oralis strain SF100]
ATGAAGAAAAAAACTAGATGGCCCTTATATGTCATCCTAGCACTAGTATTGACTTTTTTAGCATTTGTAGTACCTTTACC
TTACTACATAGAAGTTCCGGGTGGAGCGGAGGATATCCGTCGCGTTTTGAAAGTCAATGAAACAGAGGATACGGAAGCAG
GAGCTTACCAGTTTGTAACAGTTGGTATTCGACACGCAACCCTATCGCATCTTGTCTATGCTTGGTTAACACCTTTCACG
GATATTAGAAGTGCCAAGGAGACTACGGGTGGCTCTACTGATGCAGAGTTTATGCGGATCAATCAGTTTTACATGCAAAC
TTCTCAAAATATGGCCAAGTATCAAGGATTGAAGACGGCTGGTAAAGATATCGAACTCAAGTATCTTGGAGTCTATGTCT
TGACCGTGACGGACAATTCAACTTTTAAGGGTATTCTGAACATTGCAGATACTGTGACGGCTGTTAATGACAAAACATTT
GACAGTTCAAAAGACTTGGTCGACTATGTCAACTCTCAACAATTAGGGGACACGGTCAAGGTAACCTATGAAGAAGACGG
AAAAGTCAAGTCTGCAGAAGGTAAAATTATCACTCTCGAAAACGGGAAAAACGGGATTGGGATTGGCTTGATTGACCGTA
CGGAAGTGACCAGTGACGTTCCCATTCGCTTCTCTACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCCATCTATACCCAGATAGCAGATCCAGGACTTCGTAATGGCCGCATCGTTGCGGGAACGGGAACTATTGATCGCGATGG
AAATGTTGGCGACATCGGTGGAATTGACAAAAAAGTGGTTGCAGCCTCTCGTCAGGGAGCCAACATCTTTTTTGCTCCTG
ACAATCCAGTCACCGAGGAAGCAAAAAAAGCAGATCCAAATGCGAAAAGCAACTATGAAACAGCCCTAGAAGCTGCCAAA
ACGATCAAGACAGAGATGAAAATCGTTCCTGTTAAAACTTTGCAGGATGCGATTGATTACCTTAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

3D structure

• AlphaFold DB: A0A1X1GB13

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.942	99.13	0.594