Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   JRU67_RS00220 Genome accession   NZ_CP069389
Coordinates   47329..48957 (-) Length   542 a.a.
NCBI ID   WP_204178060.1    Uniprot ID   A0AB37HRK9
Organism   Mammaliicoccus sciuri strain GDQ20D70P     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 47329..95339 47329..48957 within 0


Gene organization within MGE regions


Location: 47329..95339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JRU67_RS00220 (JRU67_00220) ccrB 47329..48957 (-) 1629 WP_204178060.1 recombinase family protein Machinery gene
  JRU67_RS00225 (JRU67_00225) ccrA 48978..50327 (-) 1350 WP_196968677.1 recombinase family protein Machinery gene
  JRU67_RS00230 (JRU67_00230) - 50506..50796 (-) 291 WP_065381418.1 hypothetical protein -
  JRU67_RS00235 (JRU67_00235) - 50887..52632 (-) 1746 WP_239454541.1 DUF927 domain-containing protein -
  JRU67_RS00240 (JRU67_00240) - 52680..52970 (-) 291 WP_204168457.1 DUF1413 domain-containing protein -
  JRU67_RS00245 (JRU67_00245) - 53102..54151 (+) 1050 WP_151362626.1 ACP synthase -
  JRU67_RS15120 - 54350..54529 (+) 180 Protein_47 recombinase family protein -
  JRU67_RS00250 (JRU67_00250) - 55553..64354 (+) 8802 WP_204218645.1 YSIRK-type signal peptide-containing protein -
  JRU67_RS00255 (JRU67_00255) - 64443..64718 (+) 276 WP_239454533.1 hypothetical protein -
  JRU67_RS00260 (JRU67_00260) gtfA 64759..66261 (+) 1503 WP_204168841.1 accessory Sec system glycosyltransferase GtfA -
  JRU67_RS00265 (JRU67_00265) gtfB 66254..67585 (+) 1332 WP_204168840.1 accessory Sec system glycosylation chaperone GtfB -
  JRU67_RS00270 (JRU67_00270) - 67769..68161 (+) 393 WP_000393259.1 GNAT family N-acetyltransferase -
  JRU67_RS00275 (JRU67_00275) aph(2'')-Ia 68162..69601 (+) 1440 WP_001028144.1 aminoglycoside O-phosphotransferase APH(2'')-Ia -
  JRU67_RS00280 (JRU67_00280) - 69731..70903 (-) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  JRU67_RS00285 (JRU67_00285) - 71338..71583 (+) 246 Protein_55 arsenate reductase -
  JRU67_RS00290 (JRU67_00290) - 71898..72572 (-) 675 WP_031863792.1 IS6-like element IS257 family transposase -
  JRU67_RS00295 (JRU67_00295) - 72656..72997 (+) 342 WP_001797647.1 hydroxymethylglutaryl-CoA synthase -
  JRU67_RS00300 (JRU67_00300) - 73874..74617 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  JRU67_RS00305 (JRU67_00305) - 74714..75142 (+) 429 WP_000872606.1 MaoC family dehydratase -
  JRU67_RS00310 (JRU67_00310) mecA 75188..77197 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  JRU67_RS00315 (JRU67_00315) mecR1 77294..79051 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  JRU67_RS00320 (JRU67_00320) mecI 79051..79422 (+) 372 WP_025904161.1 mecA-type methicillin resistance repressor MecI -
  JRU67_RS00325 (JRU67_00325) psm-mec 79507..79575 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  JRU67_RS00330 (JRU67_00330) - 79895..81043 (+) 1149 WP_075773656.1 ROK family transcriptional regulator -
  JRU67_RS00335 (JRU67_00335) cstB 81157..82491 (-) 1335 Protein_65 persulfide dioxygenase-sulfurtransferase CstB -
  JRU67_RS00340 (JRU67_00340) - 82524..83588 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  JRU67_RS00345 (JRU67_00345) cstR 83724..83984 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  JRU67_RS00350 (JRU67_00350) - 83984..84622 (+) 639 Protein_68 sulfite exporter TauE/SafE family protein -
  JRU67_RS00360 (JRU67_00360) - 84896..85513 (-) 618 WP_198471753.1 CadD family cadmium resistance transporter -
  JRU67_RS00365 (JRU67_00365) - 85594..88008 (-) 2415 WP_198471754.1 heavy metal translocating P-type ATPase -
  JRU67_RS00370 (JRU67_00370) - 88001..88366 (-) 366 WP_000159127.1 metalloregulator ArsR/SmtB family transcription factor -
  JRU67_RS00375 (JRU67_00375) - 88604..88981 (-) 378 WP_140239103.1 DUF6262 family protein -
  JRU67_RS00380 (JRU67_00380) - 88988..90880 (-) 1893 WP_002485298.1 site-specific integrase -
  JRU67_RS00385 (JRU67_00385) - 91075..91398 (-) 324 WP_000088091.1 JAB domain-containing protein -
  JRU67_RS00390 (JRU67_00390) - 91391..91597 (-) 207 WP_001077283.1 hypothetical protein -
  JRU67_RS00395 (JRU67_00395) - 91599..92120 (-) 522 WP_000836008.1 DUF1643 domain-containing protein -
  JRU67_RS00400 (JRU67_00400) - 92139..92450 (-) 312 WP_000833212.1 DUF960 family protein -
  JRU67_RS00405 (JRU67_00405) - 92535..92885 (-) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  JRU67_RS00410 (JRU67_00410) - 93452..94186 (-) 735 WP_044291471.1 glucose 1-dehydrogenase -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62640.59 Da        Isoelectric Point: 9.7323

>NTDB_id=534306 JRU67_RS00220 WP_204178060.1 47329..48957(-) (ccrB) [Mammaliicoccus sciuri strain GDQ20D70P]
MQQLKQKRVGIYVRVSTEIQSSEGYSINGQINQIREYCDFNNFVVVDVYADRGISGKSMKRPELQRLLKDANEGHLDCVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSINSITYILVNPFYIGKIQFAK
YKDWNEKRRKGLNDKPIIADGKHPPIISQELWDKVQSRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQFD
EINTKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITKQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIESMDKSQLK
ALYLTVIDRIDIRKDENHKKQFYVILKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=534306 JRU67_RS00220 WP_204178060.1 47329..48957(-) (ccrB) [Mammaliicoccus sciuri strain GDQ20D70P]
ATGCAACAACTCAAACAAAAACGTGTCGGTATATATGTTCGTGTATCAACGGAAATCCAAAGTTCTGAAGGCTATAGCAT
CAATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TTTCTGGAAAATCTATGAAACGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCATCTCGATTGTGTCATG
GTGTATAAAACGAATAGACTCGCACGTAATACATCAGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAACGTATGGAAGTTAATACAAGCAGTGGTAAACTGATGCTACAAATACTTGCGAGCTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTCATGGGACAAACCCGACGTGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAATCAACATGAAGCCAATATTGTAAAATA
TATATTTGAGTCATATGCTAAAGGTCATGGTTATCGTAAAATAGCCAATGCCCTCAATCACAAAGGCTATGTTACTAAAA
AAGGTAATCCTTTTAGCATCAATTCAATAACCTATATCTTAGTCAATCCATTCTACATTGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGATTGAATGATAAACCTATTATAGCTGATGGTAAACACCCTCCTATTAT
TAGTCAAGAATTATGGGATAAAGTCCAATCACGCAAAAAACAGGTCAGTCAAAAACCTCAAGTTCATGGAAAAGGAACCA
ATCTATTAACAGGTATTATTCACTGCCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGCTATTATTCTTGTAGTAACTTTCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAAAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTTAATCAGGAGAATAAAGTCGATATCGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATTTGAT
GAAATAAATACTAAACTAAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAAACAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTACGATACGAAACAAATCGCTGCCCTGTTACAACGAATATTTCAAAATATAGAATCCATGGATAAATCACAACTCAAG
GCATTATACCTTACGGTCATTGATCGTATCGATATTCGTAAAGATGAGAATCATAAAAAGCAATTCTATGTCATACTCAA
GCTTAATAATGAAATTATTAAACAACTTTTCAATAATAATAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTT
TGCCTCAAACACTCTACTTTCAAATCTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Resolvase, N terminal domain (Resolvase)

(11-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

85.424

100

0.854