Detailed information NTG0053341

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HMPREF1038_RS04800
• Genome accession: NC_018630
• Coordinates: 887653..889893 (+)
• Length: 746 a.a.
• NCBI ID: WP_014947326.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae gamPNI0373
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 882653..894893

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF1038_RS04765 (HMPREF1038_00968)	-	882816..883784 (+)	969	WP_000658180.1	PhoH family protein	-
HMPREF1038_RS04770 (HMPREF1038_00969)	-	883964..884464 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
HMPREF1038_RS04775 (HMPREF1038_00970)	-	884467..884793 (+)	327	Protein_908	TfoX/Sxy family protein	-
HMPREF1038_RS11620 (HMPREF1038_00971)	ald	885094..886205 (-)	1112	Protein_909	alanine dehydrogenase	-
HMPREF1038_RS04790 (HMPREF1038_00973)	-	886382..886951 (+)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
HMPREF1038_RS04795 (HMPREF1038_00974)	comEA/celA/cilE	887019..887669 (+)	651	WP_000387352.1	helix-hairpin-helix domain-containing protein	Machinery gene
HMPREF1038_RS04800 (HMPREF1038_00975)	comEC/celB	887653..889893 (+)	2241	WP_014947326.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HMPREF1038_RS04805 (HMPREF1038_00976)	-	890073..890261 (+)	189	WP_010976492.1	hypothetical protein	-
HMPREF1038_RS04810 (HMPREF1038_00977)	-	890293..890880 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
HMPREF1038_RS04815 (HMPREF1038_00978)	-	890884..892059 (+)	1176	WP_000655959.1	hypothetical protein	-
HMPREF1038_RS04820 (HMPREF1038_00979)	infC	892380..892910 (+)	531	WP_025172502.1	translation initiation factor IF-3	-
HMPREF1038_RS04825 (HMPREF1038_00980)	rpmI	892943..893143 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
HMPREF1038_RS04830 (HMPREF1038_00981)	rplT	893195..893554 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
HMPREF1038_RS04835 (HMPREF1038_00982)	-	893612..893992 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84724.44 Da
• Isoelectric Point: 9.4461

>NTDB_id=53341 HMPREF1038_RS04800 WP_014947326.1 887653..889893(+) (comEC/celB) [Streptococcus pneumoniae gamPNI0373]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHLPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCVYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=53341 HMPREF1038_RS04800 WP_014947326.1 887653..889893(+) (comEC/celB) [Streptococcus pneumoniae gamPNI0373]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCATTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACCTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGTTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAAGCTTGATACCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	96.515	100	0.965
comEC/celB	Streptococcus pneumoniae D39	96.515	100	0.965
comEC/celB	Streptococcus pneumoniae R6	96.515	100	0.965
comEC/celB	Streptococcus pneumoniae TIGR4	96.515	100	0.965
comEC/celB	Streptococcus mitis SK321	91.287	100	0.913
comEC/celB	Streptococcus mitis NCTC 12261	91.007	99.866	0.909
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44