Detailed information NTG0533055

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JQC90_RS04890
• Genome accession: NZ_CP069219
• Coordinates: 1028027..1029073 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain Z0118SE0272
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1023027..1034073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQC90_RS04865	-	1024168..1024704 (+)	537	WP_001830372.1	hypothetical protein	-
JQC90_RS04870	-	1024855..1025841 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
JQC90_RS04875	map	1026015..1026770 (+)	756	WP_001830397.1	type I methionyl aminopeptidase	-
JQC90_RS04880	-	1026928..1027314 (+)	387	WP_001830382.1	hypothetical protein	-
JQC90_RS04885	liaF	1027329..1028030 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
JQC90_RS04890	vraS	1028027..1029073 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
JQC90_RS04895	vraR	1029063..1029692 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
JQC90_RS04900	-	1029749..1030927 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
JQC90_RS04905	-	1031334..1031618 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
JQC90_RS04910	-	1031626..1032090 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
JQC90_RS04915	-	1032231..1032446 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
JQC90_RS04920	-	1032448..1033689 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=533055 JQC90_RS04890 WP_001830374.1 1028027..1029073(+) (vraS) [Staphylococcus epidermidis strain Z0118SE0272]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=533055 JQC90_RS04890 WP_001830374.1 1028027..1029073(+) (vraS) [Staphylococcus epidermidis strain Z0118SE0272]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92