Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   JQC90_RS00170 Genome accession   NZ_CP069219
Coordinates   42758..44107 (-) Length   449 a.a.
NCBI ID   WP_203267717.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0272     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 41108..82701 42758..44107 within 0


Gene organization within MGE regions


Location: 41108..82701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQC90_RS00165 ccrB 41108..42736 (-) 1629 WP_203267716.1 recombinase family protein Machinery gene
  JQC90_RS00170 ccrA 42758..44107 (-) 1350 WP_203267717.1 recombinase family protein Machinery gene
  JQC90_RS00175 - 44341..46128 (-) 1788 WP_000122620.1 DUF927 domain-containing protein -
  JQC90_RS00180 - 46128..46418 (-) 291 WP_001036438.1 hypothetical protein -
  JQC90_RS00185 - 46557..47606 (+) 1050 WP_000613248.1 hypothetical protein -
  JQC90_RS00190 - 48227..49717 (+) 1491 WP_000554504.1 RNA-binding domain-containing protein -
  JQC90_RS00195 cstB 50090..51423 (-) 1334 Protein_36 persulfide dioxygenase-sulfurtransferase CstB -
  JQC90_RS00200 - 51442..52509 (-) 1068 WP_046026474.1 DsrE/DsrF/DrsH-like family protein -
  JQC90_RS00205 cstR 52648..52908 (+) 261 WP_000456194.1 persulfide-sensing transcriptional repressor CstR -
  JQC90_RS00210 - 52905..53663 (+) 759 WP_000623680.1 sulfite exporter TauE/SafE family protein -
  JQC90_RS12190 - 53879..59833 (+) 5955 WP_238990053.1 E domain-containing protein -
  JQC90_RS00230 - 59957..61573 (+) 1617 WP_046026466.1 hypothetical protein -
  JQC90_RS00235 - 61733..63244 (-) 1512 WP_203267718.1 glycosyltransferase -
  JQC90_RS00240 - 63267..64991 (-) 1725 WP_225973787.1 Mur ligase family protein -
  JQC90_RS00245 - 65040..65318 (-) 279 WP_080241884.1 hypothetical protein -
  JQC90_RS00250 - 66302..66628 (+) 327 WP_012085243.1 helix-turn-helix transcriptional regulator -
  JQC90_RS00255 - 66665..67483 (+) 819 WP_002484875.1 CPBP family intramembrane glutamic endopeptidase -
  JQC90_RS00260 - 67584..68258 (-) 675 Protein_47 IS6 family transposase -
  JQC90_RS00265 - 68342..68683 (+) 342 WP_001797647.1 hydroxymethylglutaryl-CoA synthase -
  JQC90_RS00270 - 69600..70343 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  JQC90_RS00275 - 70440..70868 (+) 429 WP_000872606.1 MaoC family dehydratase -
  JQC90_RS00280 mecA 70914..72923 (-) 2010 WP_063852638.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  JQC90_RS00285 - 73020..73127 (+) 108 Protein_52 beta-lactam sensor/signal transducer MecR1 -
  JQC90_RS00290 - 73168..73842 (+) 675 Protein_53 IS6 family transposase -
  JQC90_RS00295 - 73902..74330 (-) 429 WP_049391296.1 VOC family protein -
  JQC90_RS00300 - 74411..75340 (+) 930 WP_000750311.1 HTH domain-containing protein -
  JQC90_RS00305 - 75502..77514 (+) 2013 WP_002437507.1 hypothetical protein -
  JQC90_RS00310 - 77684..78793 (+) 1110 WP_002437509.1 DNA polymerase -
  JQC90_RS00315 - 78786..79157 (+) 372 WP_002437511.1 hypothetical protein -
  JQC90_RS00320 - 79154..80797 (+) 1644 WP_031901596.1 DUF5906 domain-containing protein -
  JQC90_RS00325 - 81022..82701 (+) 1680 WP_016187646.1 recombinase family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52635.32 Da        Isoelectric Point: 9.9585

>NTDB_id=533046 JQC90_RS00170 WP_203267717.1 42758..44107(-) (ccrA) [Staphylococcus epidermidis strain Z0118SE0272]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=533046 JQC90_RS00170 WP_203267717.1 42758..44107(-) (ccrA) [Staphylococcus epidermidis strain Z0118SE0272]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTACCATGTTCATATCTTAAGCGTACATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.327

100

0.973
  ccrA Staphylococcus aureus COL

76.169

100

0.762