Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   LA346_RS10365 Genome accession   NZ_CP083627
Coordinates   2024870..2025334 (-) Length   154 a.a.
NCBI ID   WP_001135781.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FDAARGOS_1508     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2019870..2030334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA346_RS10345 (LA346_10345) - 2020821..2021789 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  LA346_RS10350 (LA346_10350) pdrM 2021943..2023304 (-) 1362 WP_000278524.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  LA346_RS10355 (LA346_10355) - 2023315..2023575 (-) 261 WP_001105925.1 hypothetical protein -
  LA346_RS10360 (LA346_10360) - 2023589..2024857 (-) 1269 WP_000924469.1 dihydroorotase -
  LA346_RS10365 (LA346_10365) mutX 2024870..2025334 (-) 465 WP_001135781.1 8-oxo-dGTP diphosphatase Machinery gene
  LA346_RS10370 (LA346_10370) - 2025344..2025997 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  LA346_RS10375 (LA346_10375) - 2026133..2026780 (-) 648 WP_001810198.1 hypothetical protein -
  LA346_RS10380 (LA346_10380) - 2026794..2027507 (-) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  LA346_RS10385 (LA346_10385) dhaM 2027966..2028340 (-) 375 WP_000443793.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17842.19 Da        Isoelectric Point: 4.2287

>NTDB_id=532978 LA346_RS10365 WP_001135781.1 2024870..2025334(-) (mutX) [Streptococcus pneumoniae strain FDAARGOS_1508]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECATREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=532978 LA346_RS10365 WP_001135781.1 2024870..2025334(-) (mutX) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGACGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987