Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   JOS67_RS13640 Genome accession   NZ_CP069195
Coordinates   2866169..2867176 (+) Length   335 a.a.
NCBI ID   WP_065274113.1    Uniprot ID   A0AA92LQX0
Organism   Vibrio diabolicus strain SLV18     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2859745..2908940 2866169..2867176 within 0


Gene organization within MGE regions


Location: 2859745..2908940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JOS67_RS13605 (JOS67_13605) rplB 2859956..2860780 (-) 825 WP_005383168.1 50S ribosomal protein L2 -
  JOS67_RS13610 (JOS67_13610) rplW 2860796..2861098 (-) 303 WP_004398471.1 50S ribosomal protein L23 -
  JOS67_RS13615 (JOS67_13615) rplD 2861095..2861697 (-) 603 WP_005379556.1 50S ribosomal protein L4 -
  JOS67_RS13620 (JOS67_13620) rplC 2861715..2862344 (-) 630 WP_005379555.1 50S ribosomal protein L3 -
  JOS67_RS13625 (JOS67_13625) rpsJ 2862359..2862670 (-) 312 WP_005392381.1 30S ribosomal protein S10 -
  JOS67_RS13630 (JOS67_13630) rpmE 2863126..2863347 (-) 222 WP_005379546.1 50S ribosomal protein L31 -
  JOS67_RS13635 (JOS67_13635) priA 2863643..2865844 (+) 2202 WP_005392382.1 primosomal protein N' -
  JOS67_RS13640 (JOS67_13640) cytR 2866169..2867176 (+) 1008 WP_065274113.1 DNA-binding transcriptional regulator CytR Regulator
  JOS67_RS13645 (JOS67_13645) - 2867943..2867944 (-) 2 WP_407829981.1 IS630 family transposase -
  JOS67_RS13650 (JOS67_13650) tnpA 2868496..2868924 (-) 429 WP_065274109.1 IS200/IS605 family transposase -
  JOS67_RS13655 (JOS67_13655) - 2868981..2870123 (+) 1143 WP_065274108.1 RNA-guided endonuclease TnpB family protein -
  JOS67_RS13660 (JOS67_13660) ftsN 2870277..2870825 (+) 549 WP_031780671.1 cell division protein FtsN -
  JOS67_RS13665 (JOS67_13665) hslV 2870941..2871492 (+) 552 WP_203346701.1 ATP-dependent protease subunit HslV -
  JOS67_RS13670 (JOS67_13670) hslU 2871516..2872847 (+) 1332 WP_005397950.1 HslU--HslV peptidase ATPase subunit -
  JOS67_RS13675 (JOS67_13675) - 2873156..2874073 (+) 918 WP_005397953.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase -
  JOS67_RS13680 (JOS67_13680) rraA 2874150..2874656 (+) 507 WP_005397954.1 ribonuclease E activity regulator RraA -
  JOS67_RS13685 (JOS67_13685) zapB 2874792..2875034 (-) 243 WP_005379536.1 cell division protein ZapB -
  JOS67_RS13690 (JOS67_13690) glpX 2875383..2876390 (+) 1008 WP_005383180.1 class II fructose-bisphosphatase -
  JOS67_RS13695 (JOS67_13695) - 2876943..2877563 (+) 621 WP_005397957.1 helix-turn-helix transcriptional regulator -
  JOS67_RS13700 (JOS67_13700) - 2877724..2878074 (+) 351 WP_031780672.1 DUF3135 domain-containing protein -
  JOS67_RS13705 (JOS67_13705) - 2878068..2878361 (-) 294 WP_407829977.1 GIY-YIG nuclease family protein -
  JOS67_RS13710 (JOS67_13710) - 2878745..2879167 (-) 423 WP_012841178.1 DUF805 domain-containing protein -
  JOS67_RS13715 (JOS67_13715) - 2879383..2879730 (-) 348 WP_005397960.1 5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
  JOS67_RS13720 (JOS67_13720) tpiA 2880000..2880770 (+) 771 WP_005384863.1 triose-phosphate isomerase -
  JOS67_RS13725 (JOS67_13725) galU 2880868..2881746 (-) 879 WP_203346702.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  JOS67_RS13730 (JOS67_13730) - 2881815..2882981 (-) 1167 WP_203346703.1 nucleotide sugar dehydrogenase -
  JOS67_RS13735 (JOS67_13735) - 2883079..2885181 (-) 2103 WP_238935350.1 YjbH domain-containing protein -
  JOS67_RS13740 (JOS67_13740) - 2886104..2886522 (-) 419 Protein_2504 IS110 family transposase -
  JOS67_RS13745 (JOS67_13745) - 2887285..2887680 (-) 396 WP_203346704.1 type II toxin-antitoxin system death-on-curing family toxin -
  JOS67_RS13750 (JOS67_13750) - 2887680..2887850 (-) 171 WP_005397970.1 hypothetical protein -
  JOS67_RS13755 (JOS67_13755) - 2888566..2888727 (-) 162 WP_203346705.1 thrombospondin type 3 repeat-containing protein -
  JOS67_RS13760 (JOS67_13760) - 2888749..2889180 (-) 432 WP_203346706.1 hypothetical protein -
  JOS67_RS13765 (JOS67_13765) - 2889223..2890458 (-) 1236 WP_065275047.1 type II toxin-antitoxin system HipA family toxin -
  JOS67_RS13770 (JOS67_13770) - 2890451..2890726 (-) 276 WP_065274105.1 helix-turn-helix domain-containing protein -
  JOS67_RS13775 (JOS67_13775) - 2891289..2892635 (-) 1347 WP_203346707.1 ATP-binding protein -
  JOS67_RS13780 (JOS67_13780) - 2893064..2893351 (-) 288 WP_203346708.1 hypothetical protein -
  JOS67_RS13785 (JOS67_13785) - 2893696..2894109 (-) 414 WP_203346709.1 UPF0158 family protein -
  JOS67_RS24075 - 2894240..2894605 (+) 366 WP_238935351.1 hypothetical protein -
  JOS67_RS24080 - 2894527..2895153 (+) 627 WP_238935363.1 IS110 family transposase -
  JOS67_RS13795 (JOS67_13795) tnpC 2895574..2896632 (-) 1059 WP_420918321.1 IS66 family transposase -
  JOS67_RS24230 - 2896742..2897008 (-) 267 WP_411912828.1 DUF6444 domain-containing protein -
  JOS67_RS13800 (JOS67_13800) - 2897241..2897525 (+) 285 WP_203346710.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  JOS67_RS13805 (JOS67_13805) - 2897522..2897800 (+) 279 WP_203346711.1 type II toxin-antitoxin system RelE/ParE family toxin -
  JOS67_RS13810 (JOS67_13810) - 2898370..2900016 (+) 1647 WP_203346712.1 site-specific integrase -
  JOS67_RS13815 (JOS67_13815) - 2899991..2902924 (+) 2934 WP_203346713.1 site-specific integrase -
  JOS67_RS13820 (JOS67_13820) - 2902917..2904191 (+) 1275 WP_203346714.1 hypothetical protein -
  JOS67_RS13825 (JOS67_13825) - 2904440..2905600 (+) 1161 WP_203346715.1 tyrosine-type recombinase/integrase -
  JOS67_RS13830 (JOS67_13830) - 2905597..2906217 (+) 621 WP_203346716.1 hypothetical protein -
  JOS67_RS13835 (JOS67_13835) - 2906579..2907502 (-) 924 WP_203346717.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  JOS67_RS13840 (JOS67_13840) abiEi 2907495..2908034 (-) 540 WP_203347275.1 type IV toxin-antitoxin system AbiEi family antitoxin -
  JOS67_RS13845 (JOS67_13845) - 2908137..2908391 (-) 255 WP_203346718.1 hypothetical protein -

Sequence

Protein


Download         Length: 335 a.a.        Molecular weight: 36878.35 Da        Isoelectric Point: 5.9746

>NTDB_id=532840 JOS67_RS13640 WP_065274113.1 2866169..2867176(+) (cytR) [Vibrio diabolicus strain SLV18]
MATMKDVAQLAGVSTATVSRALMNPEKVSSSTRKRVEDAVLEAGYSPNSLARNLRRNESKTIVTIVPDICDPYFSEIIRG
IEDAAMEHGYLVLLGDSGQQKKRESSFVNLVFTKQADGMLLLGTDLPFDVSKPEQKNLPPMVMACEFAPELELPTVHIDN
LTSAFEAVNYLTQLGHKRIAQISGPDTAILCQFRQQGYQQALRRAGINKDPQYSVITEFSFDGGAKAVRKLLELPEPPTA
IFCHCDTMAIGAIQEAKNLGLRVPQDLSVVGFDDINFAQYCDPPLTTISQPRYEIGRQAMLMMLEMLKGHDVHSGSRLLE
TNLVIRGSAAPPQRP

Nucleotide


Download         Length: 1008 bp        

>NTDB_id=532840 JOS67_RS13640 WP_065274113.1 2866169..2867176(+) (cytR) [Vibrio diabolicus strain SLV18]
ATGGCGACAATGAAGGATGTTGCCCAGCTTGCGGGAGTGTCTACGGCTACGGTATCTCGAGCATTAATGAACCCAGAGAA
GGTCTCTTCTTCAACGAGAAAAAGAGTAGAAGATGCCGTACTTGAAGCGGGTTATTCTCCAAACTCATTAGCGCGTAACT
TACGTAGAAACGAATCAAAAACCATTGTCACTATCGTTCCCGACATCTGTGATCCTTATTTTTCTGAAATTATTCGCGGC
ATTGAAGATGCTGCCATGGAACATGGCTATCTAGTCCTGCTGGGCGATAGCGGACAACAGAAGAAACGCGAAAGTTCTTT
CGTTAACCTCGTATTTACTAAGCAGGCGGATGGAATGCTACTGCTTGGCACAGATCTACCGTTCGATGTCAGTAAGCCAG
AACAAAAGAACTTACCTCCGATGGTAATGGCGTGTGAATTTGCGCCAGAGTTAGAACTTCCGACAGTACATATTGACAAC
CTGACCTCAGCATTTGAAGCGGTGAATTACCTAACCCAACTAGGTCATAAACGCATCGCGCAAATCTCGGGGCCAGATAC
GGCAATATTGTGTCAGTTCCGCCAGCAAGGTTATCAACAAGCCTTGCGCCGCGCAGGCATCAATAAAGATCCTCAATATA
GTGTCATTACTGAGTTCTCTTTTGATGGCGGAGCAAAAGCCGTTCGTAAACTGCTCGAATTGCCTGAGCCACCAACGGCT
ATTTTCTGTCACTGTGACACAATGGCCATCGGCGCAATTCAAGAAGCGAAAAATCTTGGCTTACGAGTACCGCAAGATCT
CTCCGTTGTGGGCTTTGATGACATTAACTTCGCTCAGTACTGCGATCCACCGTTGACCACTATCTCTCAGCCTCGCTATG
AGATTGGTCGACAAGCGATGCTAATGATGCTTGAGATGTTAAAAGGACACGACGTGCATTCAGGCTCGCGCCTACTTGAA
ACTAACCTCGTCATTCGCGGAAGCGCAGCGCCACCACAGCGCCCTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, lacI family (LacI)

(3-48)

Periplasmic binding protein-like domain (Peripla_BP_3)

(168-328)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

98.204

99.701

0.979
  cytR Vibrio cholerae C6706

89.521

99.701

0.893