Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLNCDO700_RS04595 Genome accession   NZ_CP069179
Coordinates   880379..881851 (+) Length   490 a.a.
NCBI ID   WP_021037558.1    Uniprot ID   -
Organism   Lactococcus cremoris strain NCDO700     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 875379..886851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLNCDO700_RS04565 (LLNCDO700_04545) - 875855..876691 (+) 837 WP_011834858.1 metallophosphoesterase -
  LLNCDO700_RS04570 (LLNCDO700_04550) - 876784..877695 (+) 912 WP_011676635.1 CHAP domain-containing protein -
  LLNCDO700_RS04575 (LLNCDO700_04555) - 877932..878294 (+) 363 WP_011834859.1 TIGR02328 family protein -
  LLNCDO700_RS04580 (LLNCDO700_04560) - 878618..878863 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLNCDO700_RS04585 (LLNCDO700_04565) - 878996..879526 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLNCDO700_RS04590 (LLNCDO700_04570) covR 879682..880374 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLNCDO700_RS04595 (LLNCDO700_04575) covS 880379..881851 (+) 1473 WP_021037558.1 HAMP domain-containing histidine kinase Regulator
  LLNCDO700_RS04600 (LLNCDO700_04580) - 882037..883278 (+) 1242 WP_014734987.1 ammonium transporter -
  LLNCDO700_RS04605 (LLNCDO700_04585) - 883360..883701 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLNCDO700_RS04610 (LLNCDO700_04590) murD 883870..885219 (+) 1350 WP_011834864.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLNCDO700_RS04615 (LLNCDO700_04595) murG 885462..886535 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55890.74 Da        Isoelectric Point: 4.7011

>NTDB_id=532735 LLNCDO700_RS04595 WP_021037558.1 880379..881851(+) (covS) [Lactococcus cremoris strain NCDO700]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=532735 LLNCDO700_RS04595 WP_021037558.1 880379..881851(+) (covS) [Lactococcus cremoris strain NCDO700]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGATCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTAGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTGCTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947