Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | LLNCDO700_RS03145 | Genome accession | NZ_CP069179 |
| Coordinates | 600393..602843 (+) | Length | 816 a.a. |
| NCBI ID | WP_259692034.1 | Uniprot ID | - |
| Organism | Lactococcus cremoris strain NCDO700 | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 579001..622069 | 600393..602843 | within | 0 |
| IScluster/Tn | 597126..599717 | 600393..602843 | flank | 676 |
Gene organization within MGE regions
Location: 579001..622069
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LLNCDO700_RS03015 (LLNCDO700_02990) | - | 579001..579669 (+) | 669 | WP_011834609.1 | hypothetical protein | - |
| LLNCDO700_RS03020 (LLNCDO700_02995) | - | 579834..580736 (+) | 903 | WP_011675768.1 | SPFH domain-containing protein | - |
| LLNCDO700_RS03030 (LLNCDO700_03005) | - | 580985..582001 (-) | 1017 | WP_011834610.1 | site-specific integrase | - |
| LLNCDO700_RS03035 (LLNCDO700_03010) | - | 582223..582714 (-) | 492 | WP_011834611.1 | hypothetical protein | - |
| LLNCDO700_RS03040 (LLNCDO700_03015) | - | 582770..582975 (-) | 206 | Protein_571 | hypothetical protein | - |
| LLNCDO700_RS13650 | - | 582990..583585 (-) | 596 | Protein_572 | hypothetical protein | - |
| LLNCDO700_RS13655 | - | 583679..583732 (-) | 54 | Protein_573 | hypothetical protein | - |
| LLNCDO700_RS03060 (LLNCDO700_03035) | - | 583755..583931 (-) | 177 | WP_014734944.1 | hypothetical protein | - |
| LLNCDO700_RS03065 (LLNCDO700_03040) | - | 584225..585832 (+) | 1608 | WP_063284109.1 | glycosyltransferase family 39 protein | - |
| LLNCDO700_RS03070 (LLNCDO700_03045) | - | 585756..586688 (+) | 933 | WP_161769936.1 | glycosyltransferase family 2 protein | - |
| LLNCDO700_RS03075 (LLNCDO700_03050) | - | 586955..587446 (-) | 492 | WP_011834617.1 | hypothetical protein | - |
| LLNCDO700_RS03080 (LLNCDO700_03055) | - | 587459..587833 (-) | 375 | WP_011834618.1 | PH domain-containing protein | - |
| LLNCDO700_RS03085 (LLNCDO700_03060) | - | 588178..588525 (-) | 348 | WP_011834619.1 | XRE family transcriptional regulator | - |
| LLNCDO700_RS03095 (LLNCDO700_03070) | rnz | 589291..590214 (+) | 924 | WP_011834620.1 | ribonuclease Z | - |
| LLNCDO700_RS03100 (LLNCDO700_03075) | - | 590207..590908 (+) | 702 | WP_014734945.1 | SDR family oxidoreductase | - |
| LLNCDO700_RS03105 (LLNCDO700_03080) | recJ | 591081..593309 (+) | 2229 | WP_014734946.1 | single-stranded-DNA-specific exonuclease RecJ | - |
| LLNCDO700_RS03110 (LLNCDO700_03085) | - | 593433..593945 (+) | 513 | WP_011834623.1 | adenine phosphoribosyltransferase | - |
| LLNCDO700_RS03115 (LLNCDO700_03090) | rpoE | 594161..594727 (+) | 567 | WP_011834624.1 | DNA-directed RNA polymerase subunit delta | - |
| LLNCDO700_RS03120 (LLNCDO700_03095) | mltG | 594863..596503 (+) | 1641 | WP_041931175.1 | endolytic transglycosylase MltG | - |
| LLNCDO700_RS03125 (LLNCDO700_03100) | greA | 596564..597034 (+) | 471 | WP_011834626.1 | transcription elongation factor GreA | - |
| LLNCDO700_RS03130 (LLNCDO700_03105) | - | 597126..598498 (+) | 1373 | WP_289652439.1 | IS3-like element ISLla3 family transposase | - |
| LLNCDO700_RS03135 (LLNCDO700_03110) | - | 598570..599717 (+) | 1148 | WP_192824012.1 | IS3 family transposase | - |
| LLNCDO700_RS03140 (LLNCDO700_03115) | - | 599948..600403 (+) | 456 | WP_011834627.1 | CtsR family transcriptional regulator | - |
| LLNCDO700_RS03145 (LLNCDO700_03120) | clpC | 600393..602843 (+) | 2451 | WP_259692034.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| LLNCDO700_RS03150 (LLNCDO700_03125) | hpf | 602978..603535 (+) | 558 | WP_011834629.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| LLNCDO700_RS03155 (LLNCDO700_03130) | eno | 603723..605024 (+) | 1302 | WP_010905473.1 | surface-displayed alpha-enolase | - |
| LLNCDO700_RS03160 (LLNCDO700_03135) | - | 605112..606047 (+) | 936 | WP_031297127.1 | tyrosine-type recombinase/integrase | - |
| LLNCDO700_RS03165 (LLNCDO700_13670) | - | 606174..606299 (+) | 126 | WP_021213684.1 | hypothetical protein | - |
| LLNCDO700_RS03170 (LLNCDO700_03140) | - | 606320..607087 (+) | 768 | WP_010905475.1 | hypothetical protein | - |
| LLNCDO700_RS03175 (LLNCDO700_03145) | - | 607674..607814 (+) | 141 | WP_010905476.1 | hypothetical protein | - |
| LLNCDO700_RS03180 (LLNCDO700_03150) | - | 608130..608312 (+) | 183 | WP_010905477.1 | hypothetical protein | - |
| LLNCDO700_RS03185 (LLNCDO700_03155) | - | 608334..609503 (+) | 1170 | WP_010905478.1 | hypothetical protein | - |
| LLNCDO700_RS03190 (LLNCDO700_03160) | - | 610261..611151 (-) | 891 | WP_262674407.1 | IS982-like element ISLll1 family transposase | - |
| LLNCDO700_RS03195 (LLNCDO700_03165) | - | 611376..614363 (+) | 2988 | WP_259692123.1 | DEAD/DEAH box helicase family protein | - |
| LLNCDO700_RS03200 (LLNCDO700_03170) | - | 614403..615950 (+) | 1548 | WP_259692124.1 | type I restriction-modification system subunit M | - |
| LLNCDO700_RS03205 (LLNCDO700_03175) | - | 615947..617188 (+) | 1242 | WP_259692125.1 | restriction endonuclease subunit S | - |
| LLNCDO700_RS03210 (LLNCDO700_03180) | - | 617338..617607 (+) | 270 | WP_010905484.1 | hypothetical protein | - |
| LLNCDO700_RS03215 (LLNCDO700_03185) | - | 617942..618109 (+) | 168 | WP_010905485.1 | hypothetical protein | - |
| LLNCDO700_RS03220 (LLNCDO700_03190) | - | 618375..619145 (+) | 771 | WP_010905486.1 | hypothetical protein | - |
| LLNCDO700_RS03230 (LLNCDO700_03200) | - | 621190..621294 (+) | 105 | Protein_607 | hypothetical protein | - |
| LLNCDO700_RS03235 (LLNCDO700_03205) | - | 621398..622069 (-) | 672 | WP_011834634.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 816 a.a. Molecular weight: 90363.72 Da Isoelectric Point: 6.6284
>NTDB_id=532730 LLNCDO700_RS03145 WP_259692034.1 600393..602843(+) (clpC) [Lactococcus cremoris strain NCDO700]
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKNSDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKNSDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV
Nucleotide
Download Length: 2451 bp
>NTDB_id=532730 LLNCDO700_RS03145 WP_259692034.1 600393..602843(+) (clpC) [Lactococcus cremoris strain NCDO700]
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAGAAAGCAGCAGAATATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTTACTGTAGCTAGCTTTTTGGCAGTTCATAATAATGCAGAAGCAGTAGGAAC
AGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTCTTCAACTTTTGAAGTTACAAAAAATCAACATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGTGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCTCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGACTTTCAAATGGTTGGGGCAACGACTTATCATGAATACCAAAAATACATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCCATTGCTATCTTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCAGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATTGACTTGCTCGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAACTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAAATTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTAGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGACATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGGGCCCCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GCGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCTTGACGTTTTCAATATCATGTTG
CAAATTCTAGATGATGGATTTGTGACAGATACAAAGGGCCGCAAAGTTGATTTTAGAAACACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAACAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAGAAAGCAGCAGAATATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTTACTGTAGCTAGCTTTTTGGCAGTTCATAATAATGCAGAAGCAGTAGGAAC
AGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTCTTCAACTTTTGAAGTTACAAAAAATCAACATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGTGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCTCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGACTTTCAAATGGTTGGGGCAACGACTTATCATGAATACCAAAAATACATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCCATTGCTATCTTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCAGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATTGACTTGCTCGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAACTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAAATTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTAGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGACATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGGGCCCCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GCGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCTTGACGTTTTCAATATCATGTTG
CAAATTCTAGATGATGGATTTGTGACAGATACAAAGGGCCGCAAAGTTGATTTTAGAAACACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAACAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
95.833 |
100 |
0.958 |
| clpC | Streptococcus thermophilus LMD-9 |
50.903 |
100 |
0.518 |
| clpC | Streptococcus thermophilus LMG 18311 |
50.782 |
100 |
0.517 |
| clpC | Streptococcus mutans UA159 |
48.918 |
100 |
0.499 |
| clpC | Streptococcus pneumoniae Rx1 |
49.153 |
100 |
0.498 |
| clpC | Streptococcus pneumoniae D39 |
49.153 |
100 |
0.498 |
| clpC | Streptococcus pneumoniae TIGR4 |
49.031 |
100 |
0.496 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
49.876 |
98.529 |
0.491 |
| clpE | Streptococcus mutans UA159 |
46.769 |
79.657 |
0.373 |
| clpC | Lactococcus lactis subsp. cremoris KW2 |
46.248 |
80.025 |
0.37 |
| clpE | Streptococcus pneumoniae TIGR4 |
46.89 |
76.838 |
0.36 |
| clpE | Streptococcus pneumoniae Rx1 |
46.89 |
76.838 |
0.36 |
| clpE | Streptococcus pneumoniae D39 |
46.89 |
76.838 |
0.36 |
| clpE | Streptococcus pneumoniae R6 |
46.89 |
76.838 |
0.36 |