Detailed information NTG0532693

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: IS492_RS08385
• Genome accession: NZ_CP069177
• Coordinates: 1783927..1785144 (-)
• Length: 405 a.a.
• NCBI ID: WP_003107299.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain Z154
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1778927..1790144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IS492_RS08340 (IS492_08330)	-	1779111..1779560 (-)	450	WP_003094670.1	MOSC domain-containing protein	-
IS492_RS08345 (IS492_08335)	-	1779557..1780186 (-)	630	WP_003094668.1	DUF1780 domain-containing protein	-
IS492_RS08350 (IS492_08340)	-	1780319..1780744 (+)	426	WP_003103865.1	GNAT family N-acetyltransferase	-
IS492_RS08355 (IS492_08345)	-	1780741..1781211 (+)	471	WP_003094664.1	hypothetical protein	-
IS492_RS08360 (IS492_08350)	-	1781208..1781897 (+)	690	WP_003103868.1	energy-coupling factor ABC transporter permease	-
IS492_RS08365 (IS492_08355)	-	1782003..1782212 (+)	210	WP_003094660.1	hypothetical protein	-
IS492_RS08370 (IS492_08360)	yacG	1782249..1782449 (-)	201	WP_003094656.1	DNA gyrase inhibitor YacG	-
IS492_RS08375 (IS492_08365)	coaE	1782446..1783057 (-)	612	WP_003094654.1	dephospho-CoA kinase	-
IS492_RS08380 (IS492_08370)	pilD	1783054..1783926 (-)	873	WP_023084852.1	type IV prepilin peptidase/methyltransferase PilD	Machinery gene
IS492_RS08385 (IS492_08375)	pilC	1783927..1785144 (-)	1218	WP_003107299.1	type II secretion system F family protein	Machinery gene
IS492_RS08390 (IS492_08380)	pilB	1785148..1786848 (-)	1701	WP_023084853.1	type IV-A pilus assembly ATPase PilB	Machinery gene
IS492_RS08395 (IS492_08385)	-	1787079..1787543 (+)	465	WP_003107295.1	pilin	-
IS492_RS08400 (IS492_08390)	-	1787635..1788993 (+)	1359	WP_225319414.1	O-antigen ligase family protein	-
IS492_RS08410 (IS492_08400)	nadC	1789174..1790022 (-)	849	WP_003116246.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 405 a.a.
• Molecular weight: 44001.86 Da
• Isoelectric Point: 9.8103

>NTDB_id=532693 IS492_RS08385 WP_003107299.1 1783927..1785144(-) (pilC) [Pseudomonas aeruginosa strain Z154]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTMMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVGKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide

• Length: 1218 bp

>NTDB_id=532693 IS492_RS08385 WP_003107299.1 1783927..1785144(-) (pilC) [Pseudomonas aeruginosa strain Z154]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TCTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATGGACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCCGGCGTGCCGCTGCTGCAGTCGTTCGACATCATCAGCGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGA
GATCAAGCAGGAAGTCGCCGGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACT
GCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTGGAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCAGCCTTCACCATGATGG
TCATCAACATTTCCAACGTACTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCGATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGGCAAGATCAAGCAGGACGTTTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTCCCCAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
CTGGGCAACGTCGTCTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (276-397)

• Type II secretion system (T2SS), protein F (T2SSF) (71-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	78.765	100	0.788
pilC	Acinetobacter baylyi ADP1	61.029	100	0.615
pilC	Acinetobacter baumannii D1279779	60.396	99.753	0.602
pilC	Legionella pneumophila strain ERS1305867	54.293	97.778	0.531
pilG	Neisseria gonorrhoeae MS11	46.04	99.753	0.459
pilG	Neisseria meningitidis 44/76-A	45.522	99.259	0.452
pilC	Vibrio cholerae strain A1552	41.481	100	0.415
pilC	Vibrio campbellii strain DS40M4	40.648	99.012	0.402
pilC	Thermus thermophilus HB27	38.155	99.012	0.378